3w7r: Difference between revisions

Line 1:

~~'''Unreleased structure'''~~

===Structure of Human dihydroorotate dehydrogenase in complex with mii-4-097===

~~The~~ entry ~~3w7r~~ is ~~ON HOLD~~ ~~until Paper Publication~~

==Disease==

[[http://www.uniprot.org/uniprot/PYRD_HUMAN PYRD_HUMAN]] Defects in DHODH are the cause of postaxial acrofacial dysostosis (POADS) [MIM:[http://omim.org/entry/263750 263750]]; also known as Miller syndrome. POADS is characterized by severe micrognathia, cleft lip and/or palate, hypoplasia or aplasia of the posterior elements of the limbs, coloboma of the eyelids and supernumerary nipples. POADS is a very rare disorder: only 2 multiplex families, each consisting of 2 affected siblings born to unaffected, nonconsanguineous parents, have been described among a total of around 30 reported cases.<ref>PMID:19915526</ref>

~~Authors~~: ~~Inaoka, D~~.K., Iida, M., Tabuchi, T., Lee, N., Hashimoto, S., Matsuoka, S., Kuranaga, T., Shiba, T., Sakamoto, K., Suzuki, S., Balogun, E.O., Nara, T., Aoki, T., Inoue, M., Honma, T., Tanaka, A., Harada, S., Kita, K.

==Function==

[[http://www.uniprot.org/uniprot/PYRD_HUMAN PYRD_HUMAN]] Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor.

~~Description~~: ~~Structure of Human dihydroorotate dehydrogenase in complex with mii~~-4-~~097~~

==About this Structure==

[[3w7r]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3W7R OCA].

==Reference==

[[Category: Aoki, T.]]

[[Category: Balogun, E O.]]

[[Category: Harada, S.]]

[[Category: Hashimoto, S.]]

[[Category: Honma, T.]]

[[Category: Iida, M.]]

[[Category: Inaoka, D K.]]

[[Category: Inoue, M.]]

[[Category: Kita, K.]]

[[Category: Kuranaga, T.]]

[[Category: Lee, N.]]

[[Category: Matsuoka, S.]]

[[Category: Nara, T.]]

[[Category: Sakamoto, K.]]

[[Category: Shiba, T.]]

[[Category: Suzuki, S.]]

[[Category: Tabuchi, T.]]

[[Category: Tanaka, A.]]

[[Category: Dihydroorotate/orotate and ubiquinone/ubiquinol]]

[[Category: Mitochondrial inner membrane]]

[[Category: Oxidoreductase]]

[[Category: Oxidoreductase-oxidoreductase inhibitor complex]]

[[Category: Rossmann fold]]

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@@ Line 1: / Line 1: @@
-'''Unreleased structure'''
+{{STRUCTURE_3w7r|  PDB=3w7r  |  SCENE=  }}
+===Structure of Human dihydroorotate dehydrogenase in complex with mii-4-097===
-The entry 3w7r is ON HOLD  until Paper Publication
+==Disease==
+[[http://www.uniprot.org/uniprot/PYRD_HUMAN PYRD_HUMAN]] Defects in DHODH are the cause of postaxial acrofacial dysostosis (POADS) [MIM:[http://omim.org/entry/263750 263750]]; also known as Miller syndrome. POADS is characterized by severe micrognathia, cleft lip and/or palate, hypoplasia or aplasia of the posterior elements of the limbs, coloboma of the eyelids and supernumerary nipples. POADS is a very rare disorder: only 2 multiplex families, each consisting of 2 affected siblings born to unaffected, nonconsanguineous parents, have been described among a total of around 30 reported cases.<ref>PMID:19915526</ref>
-Authors: Inaoka, D.K., Iida, M., Tabuchi, T., Lee, N., Hashimoto, S., Matsuoka, S., Kuranaga, T., Shiba, T., Sakamoto, K., Suzuki, S., Balogun, E.O., Nara, T., Aoki, T., Inoue, M., Honma, T., Tanaka, A., Harada, S., Kita, K.
+==Function==
+[[http://www.uniprot.org/uniprot/PYRD_HUMAN PYRD_HUMAN]] Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor.
-Description: Structure of Human dihydroorotate dehydrogenase in complex with mii-4-097
+==About this Structure==
+[[3w7r]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3W7R OCA].
+==Reference==
+<references group="xtra"/><references/>
+[[Category: Aoki, T.]]
+[[Category: Balogun, E O.]]
+[[Category: Harada, S.]]
+[[Category: Hashimoto, S.]]
+[[Category: Honma, T.]]
+[[Category: Iida, M.]]
+[[Category: Inaoka, D K.]]
+[[Category: Inoue, M.]]
+[[Category: Kita, K.]]
+[[Category: Kuranaga, T.]]
+[[Category: Lee, N.]]
+[[Category: Matsuoka, S.]]
+[[Category: Nara, T.]]
+[[Category: Sakamoto, K.]]
+[[Category: Shiba, T.]]
+[[Category: Suzuki, S.]]
+[[Category: Tabuchi, T.]]
+[[Category: Tanaka, A.]]
+[[Category: Dihydroorotate/orotate and ubiquinone/ubiquinol]]
+[[Category: Mitochondrial inner membrane]]
+[[Category: Oxidoreductase]]
+[[Category: Oxidoreductase-oxidoreductase inhibitor complex]]
+[[Category: Rossmann fold]]