3wam: Difference between revisions
From Proteopedia
Jump to navigationJump to search
No edit summary |
No edit summary |
||
| Line 1: | Line 1: | ||
{{STRUCTURE_3wam| PDB=3wam | SCENE= }} | |||
===Crystal structure of human LC3C_8-125=== | |||
{{ABSTRACT_PUBMED_24290141}} | |||
==Function== | |||
[[http://www.uniprot.org/uniprot/MLP3C_HUMAN MLP3C_HUMAN]] Ubiquitin-like modifier that plays a crucial role in antibacterial autophagy (xenophagy) through the selective binding of CALCOCO2. Recruites all ATG8 family members to infecting bacteria such as S.Typhimurium.<ref>PMID:23022382</ref> | |||
==About this Structure== | |||
[[3wam]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3WAM OCA]. | |||
==Reference== | |||
<ref group="xtra">PMID:024290141</ref><references group="xtra"/><references/> | |||
[[Category: Dobson, R C.J.]] | |||
[[Category: Kato, R.]] | |||
[[Category: Kawasaki, M.]] | |||
[[Category: Morita, E.]] | |||
[[Category: Suzuki, H.]] | |||
[[Category: Tabata, K.]] | |||
[[Category: Wakatsuki, S.]] | |||
[[Category: Yoshimori, T.]] | |||
[[Category: Autophagy]] | |||
[[Category: Protein transport]] | |||
[[Category: Ubiquitin-like fold]] | |||
Revision as of 10:19, 25 December 2013
Crystal structure of human LC3C_8-125
Template:ABSTRACT PUBMED 24290141
Function
[MLP3C_HUMAN] Ubiquitin-like modifier that plays a crucial role in antibacterial autophagy (xenophagy) through the selective binding of CALCOCO2. Recruites all ATG8 family members to infecting bacteria such as S.Typhimurium.[1]
About this Structure
3wam is a 1 chain structure. Full crystallographic information is available from OCA.
Reference
- Suzuki H, Tabata K, Morita E, Kawasaki M, Kato R, Dobson RC, Yoshimori T, Wakatsuki S. Structural Basis of the Autophagy-Related LC3/Atg13 LIR Complex: Recognition and Interaction Mechanism. Structure. 2013 Nov 25. pii: S0969-2126(13)00401-2. doi:, 10.1016/j.str.2013.09.023. PMID:24290141 doi:https://dx.doi.org/10.1016/j.str.2013.09.023
- ↑ von Muhlinen N, Akutsu M, Ravenhill BJ, Foeglein A, Bloor S, Rutherford TJ, Freund SM, Komander D, Randow F. LC3C, bound selectively by a noncanonical LIR motif in NDP52, is required for antibacterial autophagy. Mol Cell. 2012 Nov 9;48(3):329-42. doi: 10.1016/j.molcel.2012.08.024. Epub 2012, Sep 27. PMID:23022382 doi:https://dx.doi.org/10.1016/j.molcel.2012.08.024
