4bvc: Difference between revisions

Line 1:

'''~~Unreleased structure~~'''

==Identification of small molecule inhibitors selective for apo(a) kringles KIV-7, KIV-10 and KV.==

~~The entry~~ 4bvc is ~~ON HOLD until Paper Publication~~

== Structural highlights ==

<table><tr><td colspan='2'>[[4bvc]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4BVC OCA]. For a guided tour on the structure components use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4BVC FirstGlance].

~~Authors~~: ~~Sandmark~~, J., Althage, M., Andersson, G.M.K., Antonsson, T., Blaho, S., Bodin, C., Bostrom, J., Chen, Y., Dahlen, A., Eriksson, P.O., Evertsson, E., Fex, T., Fjellstrom, O., Gustafsson, D., Hallberg, C., Hicks, R., Jarkvist, E., Johansson, C., Kalies, I., Kang, D.~~, Svalstedt~~ Karlsson, B., Kartberg, F., Legnehed, A., Lindqvist, A.M., Martinsson, S.A., Moberg, A., Petersson, A.U., Ridderstrom, M., Thelin, A., Tigerstrom, A., Vinblad, J., Xu, B.~~, Knecht, W.~~

</td></tr><tr><td class="sblockLbl">[[Ligand|Ligands:]]</td><td class="sblockDat"><scene name='pdbligand=BV5:3-(4-PIPERIDYL)-N-[2-(TRIFLUOROMETHOXY)PHENYL]SULFONYL-PROPANAMIDE'>BV5</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene>

~~Description~~: ~~Identification of small molecule inhibitors selective for apo(a) kringles KIV-7, KIV-10 and KV.~~

<tr><td class="sblockLbl">Resources:</td><td class="sblockDat">[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4bvc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4bvc OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4bvc RCSB], [http://www.ebi.ac.uk/pdbsum/4bvc PDBsum]</td></tr>

<table>

__TOC__

</StructureSection>

[[Category: Althage, M.]]

[[Category: Andersson, G M.K.]]

[[Category: Antonsson, T.]]

[[Category: Blaho, S.]]

[[Category: Bodin, C.]]

[[Category: Bostrom, J.]]

[[Category: Chen, Y.]]

[[Category: Dahlen, A.]]

[[Category: Eriksson, P O.]]

[[Category: Evertsson, E.]]

[[Category: Fex, T.]]

[[Category: Fjellstrom, O.]]

[[Category: Gustafsson, D.]]

[[Category: Hallberg, C.]]

[[Category: Hicks, R.]]

[[Category: Jarkvist, E.]]

[[Category: Johansson, C.]]

[[Category: Kalies, I.]]

[[Category: Kang, D.]]

[[Category: Karlsson, B Svalstedt.]]

[[Category: Kartberg, F.]]

[[Category: Knecht, W.]]

[[Category: Legnehed, A.]]

[[Category: Lindqvist, A M.]]

[[Category: Martinsson, S A.]]

[[Category: Moberg, A.]]

[[Category: Petersson, A U.]]

[[Category: Ridderstrom, M.]]

[[Category: Sandmark, J.]]

[[Category: Thelin, A.]]

[[Category: Tigerstrom, A.]]

[[Category: Vinblad, J.]]

[[Category: Xu, B.]]

[[Category: Cardiovascular disease]]

[[Category: Drug discovery]]

[[Category: Hydrolase]]

[[Category: Optical biosensor]]

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@@ Line 1: / Line 1: @@
-'''Unreleased structure'''
+==Identification of small molecule inhibitors selective for apo(a) kringles KIV-7, KIV-10 and KV.==
+<StructureSection load='4bvc' size='340' side='right' caption='[[4bvc]], [[Resolution|resolution]] 1.60&Aring;' scene=''>
-The entry 4bvc is ON HOLD  until Paper Publication
+== Structural highlights ==
+<table><tr><td colspan='2'>[[4bvc]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4BVC OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4BVC FirstGlance]. <br>
-Authors: Sandmark, J., Althage, M., Andersson, G.M.K., Antonsson, T., Blaho, S., Bodin, C., Bostrom, J., Chen, Y., Dahlen, A., Eriksson, P.O., Evertsson, E., Fex, T., Fjellstrom, O., Gustafsson, D., Hallberg, C., Hicks, R., Jarkvist, E., Johansson, C., Kalies, I., Kang, D., Svalstedt Karlsson, B., Kartberg, F., Legnehed, A., Lindqvist, A.M., Martinsson, S.A., Moberg, A., Petersson, A.U., Ridderstrom, M., Thelin, A., Tigerstrom, A., Vinblad, J., Xu, B., Knecht, W.
+</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=BV5:3-(4-PIPERIDYL)-N-[2-(TRIFLUOROMETHOXY)PHENYL]SULFONYL-PROPANAMIDE'>BV5</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene><br>
+<tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4bv5|4bv5]], [[4bv7|4bv7]], [[4bvd|4bvd]], [[4bvv|4bvv]], [[4bvw|4bvw]]</td></tr>
-Description: Identification of small molecule inhibitors selective for apo(a) kringles KIV-7, KIV-10 and KV.
+<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4bvc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4bvc OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4bvc RCSB], [http://www.ebi.ac.uk/pdbsum/4bvc PDBsum]</span></td></tr>
+<table>
+__TOC__
+</StructureSection>
+[[Category: Althage, M.]]
+[[Category: Andersson, G M.K.]]
+[[Category: Antonsson, T.]]
+[[Category: Blaho, S.]]
+[[Category: Bodin, C.]]
+[[Category: Bostrom, J.]]
+[[Category: Chen, Y.]]
+[[Category: Dahlen, A.]]
+[[Category: Eriksson, P O.]]
+[[Category: Evertsson, E.]]
+[[Category: Fex, T.]]
+[[Category: Fjellstrom, O.]]
+[[Category: Gustafsson, D.]]
+[[Category: Hallberg, C.]]
+[[Category: Hicks, R.]]
+[[Category: Jarkvist, E.]]
+[[Category: Johansson, C.]]
+[[Category: Kalies, I.]]
+[[Category: Kang, D.]]
+[[Category: Karlsson, B Svalstedt.]]
+[[Category: Kartberg, F.]]
+[[Category: Knecht, W.]]
+[[Category: Legnehed, A.]]
+[[Category: Lindqvist, A M.]]
+[[Category: Martinsson, S A.]]
+[[Category: Moberg, A.]]
+[[Category: Petersson, A U.]]
+[[Category: Ridderstrom, M.]]
+[[Category: Sandmark, J.]]
+[[Category: Thelin, A.]]
+[[Category: Tigerstrom, A.]]
+[[Category: Vinblad, J.]]
+[[Category: Xu, B.]]
+[[Category: Cardiovascular disease]]
+[[Category: Drug discovery]]
+[[Category: Hydrolase]]
+[[Category: Optical biosensor]]