4hpw: Difference between revisions

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'''Unreleased structure'''
{{STRUCTURE_4hpw|  PDB=4hpw  |  SCENE=  }}
===Crystal structure of Tyrosine-tRNA ligase mutant complexed with unnatural amino acid 3-o-methyl-Tyrosine===


The entry 4hpw is ON HOLD until Oct 24 2014
==Function==
[[http://www.uniprot.org/uniprot/SYY_METJA SYY_METJA]] Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).<ref>PMID:10585437</ref>  


Authors: Yang, Y., Zhou, Q., Dong, J., Li, J., Xiaoxuan, L., Mukherjee, A., Ouyang, H., Nilges, M., Li, H., Gao, F., Gong, W., Lu, Y., Wang, J.
==About this Structure==
[[4hpw]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Methanocaldococcus_jannaschii_dsm_2661 Methanocaldococcus jannaschii dsm 2661]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4HPW OCA].  


Description: Crystal structure of Tyrosine-tRNA ligase mutant complexed with unnatural amino acid 3-o-methyl-Tyrosine
==Reference==
<references group="xtra"/><references/>
[[Category: Methanocaldococcus jannaschii dsm 2661]]
[[Category: Tyrosine--tRNA ligase]]
[[Category: Dong, J.]]
[[Category: Gao, F.]]
[[Category: Gong, W.]]
[[Category: Li, H.]]
[[Category: Li, J.]]
[[Category: Lu, Y.]]
[[Category: Mukherjee, A.]]
[[Category: Nilges, M.]]
[[Category: Ouyang, H.]]
[[Category: Wang, J.]]
[[Category: Xiaoxuan, L.]]
[[Category: Yang, Y.]]
[[Category: Zhou, Q.]]
[[Category: 3-o-methyl tyrosine incorporation]]
[[Category: Ligase]]
[[Category: Trna]]

Revision as of 09:50, 30 October 2013

Template:STRUCTURE 4hpw

Crystal structure of Tyrosine-tRNA ligase mutant complexed with unnatural amino acid 3-o-methyl-Tyrosine

Function

[SYY_METJA] Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).[1]

About this Structure

4hpw is a 1 chain structure with sequence from Methanocaldococcus jannaschii dsm 2661. Full crystallographic information is available from OCA.

Reference

  1. ↑ Steer BA, Schimmel P. Major anticodon-binding region missing from an archaebacterial tRNA synthetase. J Biol Chem. 1999 Dec 10;274(50):35601-6. PMID:10585437

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