4l1o: Difference between revisions
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{{STRUCTURE_4l1o| PDB=4l1o | SCENE= }} | |||
===Crystal structure of human ALDH3A1 with inhibitor 1-{[4-(1,3-benzodioxol-5-ylmethyl)piperazin-1-yl]methyl}-1H-indole-2,3-dione=== | |||
==Function== | |||
[[http://www.uniprot.org/uniprot/AL3A1_HUMAN AL3A1_HUMAN]] ALDHs play a major role in the detoxification of alcohol-derived acetaldehyde. They are involved in the metabolism of corticosteroids, biogenic amines, neurotransmitters, and lipid peroxidation. This protein preferentially oxidizes aromatic aldehyde substrates. It may play a role in the oxidation of toxic aldehydes. | |||
==About this Structure== | |||
[[4l1o]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4L1O OCA]. | |||
[[Category: Hurley, T D.]] | |||
[[Category: Parajuli, B.]] | |||
[[Category: Catalyzes benzaldehyde]] | |||
[[Category: Dehydrogenase]] | |||
[[Category: Nadp+ binding]] | |||
[[Category: Oxidoreductase-inhibitor complex]] | |||
[[Category: Rossman fold]] | |||