4l1o: Difference between revisions

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'''Unreleased structure'''
{{STRUCTURE_4l1o|  PDB=4l1o  |  SCENE=  }}
===Crystal structure of human ALDH3A1 with inhibitor 1-{[4-(1,3-benzodioxol-5-ylmethyl)piperazin-1-yl]methyl}-1H-indole-2,3-dione===


The entry 4l1o is ON HOLD  until Paper Publication
==Function==
[[http://www.uniprot.org/uniprot/AL3A1_HUMAN AL3A1_HUMAN]] ALDHs play a major role in the detoxification of alcohol-derived acetaldehyde. They are involved in the metabolism of corticosteroids, biogenic amines, neurotransmitters, and lipid peroxidation. This protein preferentially oxidizes aromatic aldehyde substrates. It may play a role in the oxidation of toxic aldehydes.


Authors: Hurley, T.D., Parajuli, B.
==About this Structure==
 
[[4l1o]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4L1O OCA].
Description: Crystal structure of human ALDH3A1 with inhibitor 1-{[4-(1,3-benzodioxol-5-ylmethyl)piperazin-1-yl]methyl}-1H-indole-2,3-dione
[[Category: Hurley, T D.]]
[[Category: Parajuli, B.]]
[[Category: Catalyzes benzaldehyde]]
[[Category: Dehydrogenase]]
[[Category: Nadp+ binding]]
[[Category: Oxidoreductase-inhibitor complex]]
[[Category: Rossman fold]]