4lb2: Difference between revisions

Line 1:

~~'''Unreleased structure'''~~

===X-ray study of human serum albumin complexed with idarubicin===

~~The~~ entry ~~4lb2~~ is ~~ON HOLD~~

==Disease==

[[http://www.uniprot.org/uniprot/ALBU_HUMAN ALBU_HUMAN]] Defects in ALB are a cause of familial dysalbuminemic hyperthyroxinemia (FDH) [MIM:[http://omim.org/entry/103600 103600]]. FDH is a form of euthyroid hyperthyroxinemia that is due to increased affinity of ALB for T(4). It is the most common cause of inherited euthyroid hyperthyroxinemia in Caucasian population.<ref>PMID:8048949</ref> <ref>PMID:7852505</ref> <ref>PMID:9329347</ref> <ref>PMID:9589637</ref>

~~Authors~~: ~~Wang~~, Z., Ho, ~~J.X.~~, ~~Ruble~~, J., ~~Rose~~, J.P., ~~Carter, D.C~~.

==Function==

[[http://www.uniprot.org/uniprot/ALBU_HUMAN ALBU_HUMAN]] Serum albumin, the main protein of plasma, has a good binding capacity for water, Ca(2+), Na(+), K(+), fatty acids, hormones, bilirubin and drugs. Its main function is the regulation of the colloidal osmotic pressure of blood. Major zinc transporter in plasma, typically binds about 80% of all plasma zinc.<ref>PMID:19021548</ref>

~~Description~~: X~~-ray study of human serum albumin complexed with idarubicin~~

==About this Structure==

[[4lb2]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4LB2 OCA].

==Reference==

[[Category: Homo sapiens]]

[[Category: Carter, D C.]]

[[Category: Ho, J X.]]

[[Category: Rose, J P.]]

[[Category: Ruble, J.]]

[[Category: Wang, Z.]]

[[Category: Cancer]]

[[Category: Oncology drug complex]]

[[Category: Plasma protein]]

[[Category: Transport protein]]

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@@ Line 1: / Line 1: @@
-'''Unreleased structure'''
+{{STRUCTURE_4lb2|  PDB=4lb2  |  SCENE=  }}
+===X-ray study of human serum albumin complexed with idarubicin===
+{{ABSTRACT_PUBMED_23838380}}
-The entry 4lb2 is ON HOLD
+==Disease==
+[[http://www.uniprot.org/uniprot/ALBU_HUMAN ALBU_HUMAN]] Defects in ALB are a cause of familial dysalbuminemic hyperthyroxinemia (FDH) [MIM:[http://omim.org/entry/103600 103600]]. FDH is a form of euthyroid hyperthyroxinemia that is due to increased affinity of ALB for T(4). It is the most common cause of inherited euthyroid hyperthyroxinemia in Caucasian population.<ref>PMID:8048949</ref> <ref>PMID:7852505</ref> <ref>PMID:9329347</ref> <ref>PMID:9589637</ref>
-Authors: Wang, Z., Ho, J.X., Ruble, J., Rose, J.P., Carter, D.C.
+==Function==
+[[http://www.uniprot.org/uniprot/ALBU_HUMAN ALBU_HUMAN]] Serum albumin, the main protein of plasma, has a good binding capacity for water, Ca(2+), Na(+), K(+), fatty acids, hormones, bilirubin and drugs. Its main function is the regulation of the colloidal osmotic pressure of blood. Major zinc transporter in plasma, typically binds about 80% of all plasma zinc.<ref>PMID:19021548</ref>
-Description: X-ray study of human serum albumin complexed with idarubicin
+==About this Structure==
+[[4lb2]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4LB2 OCA].
+==Reference==
+<ref group="xtra">PMID:023838380</ref><references group="xtra"/><references/>
+[[Category: Homo sapiens]]
+[[Category: Carter, D C.]]
+[[Category: Ho, J X.]]
+[[Category: Rose, J P.]]
+[[Category: Ruble, J.]]
+[[Category: Wang, Z.]]
+[[Category: Cancer]]
+[[Category: Oncology drug complex]]
+[[Category: Plasma protein]]
+[[Category: Transport protein]]