4lg8: Difference between revisions

Line 1:

~~'''Unreleased~~ structure~~'''~~

===Crystal structure of PRPF19 WD40 repeats===

The ~~entry 4lg8~~ is ~~ON HOLD~~

==Function==

[[http://www.uniprot.org/uniprot/PRP19_HUMAN PRP19_HUMAN]] Plays a role in DNA double-strand break (DSB) repair. Binds double-stranded DNA in a sequence-nonspecific manner. Acts as a structural component of the nuclear framework. May also serve as a support for spliceosome binding and activity. Essential for spliceosome assembly in a oligomerization-dependent manner and might also be important for spliceosome stability. May have E3 ubiquitin ligase activity. The PSO4 complex is required in the DNA interstrand cross-links (ICLs) repair process. Component of the PRP19-CDC5L complex that forms an integral part of the spliceosome and is required for activating pre-mRNA splicing.<ref>PMID:11082287</ref> <ref>PMID:12960389</ref> <ref>PMID:16332694</ref> <ref>PMID:15660529</ref> <ref>PMID:16223718</ref> <ref>PMID:16388800</ref>

~~Authors~~: ~~Xu, C~~.~~, Tempel, W~~.~~, He, H~~.~~, Dobrovetsky, E., Bountra, C., Arrowsmith, C.H~~.~~, Edwards, A~~.M.~~, Min, J~~.~~, Structural Genomics Consortium (SGC)~~

==About this Structure==

[[4lg8]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4LG8 OCA].

~~Description~~: ~~Crystal structure of PRPF19 WD40 repeats~~

==Reference==

[[Category: Homo sapiens]]

[[Category: Arrowsmith, C H.]]

[[Category: Bountra, C.]]

[[Category: Dobrovetsky, E.]]

[[Category: Edwards, A M.]]

[[Category: He, H.]]

[[Category: Min, J.]]

[[Category: SGC, Structural Genomics Consortium.]]

[[Category: Tempel, W.]]

[[Category: Xu, C.]]

[[Category: Dna binding protein]]

[[Category: Sgc]]

[[Category: Structural genomics consortium]]

[[Category: Wd40 repeat]]

Navigation menu

Page actions

Page actions

Personal tools

Navigation

Search

Tools

@@ Line 1: / Line 1: @@
-'''Unreleased structure'''
+{{STRUCTURE_4lg8|  PDB=4lg8  |  SCENE=  }}
+===Crystal structure of PRPF19 WD40 repeats===
-The entry 4lg8 is ON HOLD
+==Function==
+[[http://www.uniprot.org/uniprot/PRP19_HUMAN PRP19_HUMAN]] Plays a role in DNA double-strand break (DSB) repair. Binds double-stranded DNA in a sequence-nonspecific manner. Acts as a structural component of the nuclear framework. May also serve as a support for spliceosome binding and activity. Essential for spliceosome assembly in a oligomerization-dependent manner and might also be important for spliceosome stability. May have E3 ubiquitin ligase activity. The PSO4 complex is required in the DNA interstrand cross-links (ICLs) repair process. Component of the PRP19-CDC5L complex that forms an integral part of the spliceosome and is required for activating pre-mRNA splicing.<ref>PMID:11082287</ref> <ref>PMID:12960389</ref> <ref>PMID:16332694</ref> <ref>PMID:15660529</ref> <ref>PMID:16223718</ref> <ref>PMID:16388800</ref>
-Authors: Xu, C., Tempel, W., He, H., Dobrovetsky, E., Bountra, C., Arrowsmith, C.H., Edwards, A.M., Min, J., Structural Genomics Consortium (SGC)
+==About this Structure==
+[[4lg8]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4LG8 OCA].
-Description: Crystal structure of PRPF19 WD40 repeats
+==Reference==
+<references group="xtra"/><references/>
+[[Category: Homo sapiens]]
+[[Category: Arrowsmith, C H.]]
+[[Category: Bountra, C.]]
+[[Category: Dobrovetsky, E.]]
+[[Category: Edwards, A M.]]
+[[Category: He, H.]]
+[[Category: Min, J.]]
+[[Category: SGC, Structural Genomics Consortium.]]
+[[Category: Tempel, W.]]
+[[Category: Xu, C.]]
+[[Category: Dna binding protein]]
+[[Category: Sgc]]
+[[Category: Structural genomics consortium]]
+[[Category: Wd40 repeat]]