2ifd: Difference between revisions

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[[Image:2ifd.jpg|left|200px]]<br /><applet load="2ifd" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:2ifd.jpg|left|200px]]
caption="2ifd, resolution 2.00&Aring;" />
 
'''Crystal structure of a remote binding site mutant, R492L, of CDC25B Phosphatase catalytic domain'''<br />
{{Structure
|PDB= 2ifd |SIZE=350|CAPTION= <scene name='initialview01'>2ifd</scene>, resolution 2.00&Aring;
|SITE=
|LIGAND= <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene> and <scene name='pdbligand=CL:CHLORIDE ION'>CL</scene>
|ACTIVITY= [http://en.wikipedia.org/wiki/Protein-tyrosine-phosphatase Protein-tyrosine-phosphatase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.3.48 3.1.3.48]
|GENE= CDC25B, CDC25HU2 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])
}}
 
'''Crystal structure of a remote binding site mutant, R492L, of CDC25B Phosphatase catalytic domain'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
2IFD is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] with <scene name='pdbligand=SO4:'>SO4</scene> and <scene name='pdbligand=CL:'>CL</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/Protein-tyrosine-phosphatase Protein-tyrosine-phosphatase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.3.48 3.1.3.48] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2IFD OCA].  
2IFD is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2IFD OCA].  


==Reference==
==Reference==
Kinetic and structural studies of specific protein-protein interactions in substrate catalysis by Cdc25B phosphatase., Sohn J, Buhrman G, Rudolph J, Biochemistry. 2007 Jan 23;46(3):807-18. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=17223702 17223702]
Kinetic and structural studies of specific protein-protein interactions in substrate catalysis by Cdc25B phosphatase., Sohn J, Buhrman G, Rudolph J, Biochemistry. 2007 Jan 23;46(3):807-18. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/17223702 17223702]
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Protein-tyrosine-phosphatase]]
[[Category: Protein-tyrosine-phosphatase]]
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[[Category: phosphatase]]
[[Category: phosphatase]]


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