4atv: Difference between revisions

Line 1:

~~{{STRUCTURE_4atv| PDB=4atv | SCENE= }}~~

==STRUCTURE OF A TRIPLE MUTANT OF THE NHAA DIMER, CRYSTALLISED AT LOW PH==

===STRUCTURE OF A TRIPLE MUTANT OF THE NHAA DIMER, CRYSTALLISED AT LOW PH===

== Structural highlights ==

==~~Function~~==

<table><tr><td colspan='2'>[[4atv]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4ATV OCA]. For a guided tour on the structure components use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4ATV FirstGlance].

[[~~http://www.uniprot.org/uniprot/NHAA_ECOLI NHAA_ECOLI~~]] ~~Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons~~. ~~Catalyzes the exchange of 2 H(+) per Na(+). Can mediate sodium uptake when a transmembrane pH gradient is applied. Active at alkaline pH. Activity is strongly down-regulated below pH 6.5.<ref~~>~~PMID:1645730</ref>~~

</td></tr><tr id='ligand'><td class="sblockLbl">[[Ligand|Ligands:]]</td><td class="sblockDat"><scene name='pdbligand=LMU:DODECYL-ALPHA-D-MALTOSIDE'>LMU</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>

<tr id='NonStdRes'><td class="sblockLbl">[[Non-Standard_Residue|NonStd Res:]]</td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>

==~~About this Structure~~==

<tr id='related'><td class="sblockLbl">[[Related_structure|Related:]]</td><td class="sblockDat">[[1zcd|1zcd]]</td></tr>

[[4atv]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4ATV OCA].

<tr id='resources'><td class="sblockLbl">Resources:</td><td class="sblockDat">[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4atv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4atv OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4atv RCSB], [http://www.ebi.ac.uk/pdbsum/4atv PDBsum]</td></tr>

</table>

==~~Reference~~==

__TOC__

<~~references group~~="~~xtra~~"/><~~references~~/>

</StructureSection>

[[Category: Escherichia coli]]

[[Category: Cameron, A D.]]

[[Category: Cameron, A D]]

[[Category: Drew, D.]]

[[Category: Drew, D]]

[[Category: Iwata, S.]]

[[Category: Iwata, S]]

[[Category: Lee, C.]]

[[Category: Lee, C]]

[[Category: Membrane protein]]

[[Category: Sodium proton antiporter]]

[[Category: Transporter]]

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@@ Line 1: / Line 1: @@
-{{STRUCTURE_4atv|  PDB=4atv  |  SCENE=  }}
+==STRUCTURE OF A TRIPLE MUTANT OF THE NHAA DIMER, CRYSTALLISED AT LOW PH==
-===STRUCTURE OF A TRIPLE MUTANT OF THE NHAA DIMER, CRYSTALLISED AT LOW PH===
+<StructureSection load='4atv' size='340' side='right' caption='[[4atv]], [[Resolution|resolution]] 3.50&Aring;' scene=''>
+== Structural highlights ==
-==Function==
+<table><tr><td colspan='2'>[[4atv]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4ATV OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4ATV FirstGlance]. <br>
-[[http://www.uniprot.org/uniprot/NHAA_ECOLI NHAA_ECOLI]] Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons. Catalyzes the exchange of 2 H(+) per Na(+). Can mediate sodium uptake when a transmembrane pH gradient is applied. Active at alkaline pH. Activity is strongly down-regulated below pH 6.5.<ref>PMID:1645730</ref>
+</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=LMU:DODECYL-ALPHA-D-MALTOSIDE'>LMU</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
+<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
-==About this Structure==
+<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1zcd|1zcd]]</td></tr>
-[[4atv]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4ATV OCA].
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4atv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4atv OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4atv RCSB], [http://www.ebi.ac.uk/pdbsum/4atv PDBsum]</span></td></tr>
+</table>
-==Reference==
+__TOC__
-<references group="xtra"/><references/>
+</StructureSection>
 [[Category: Escherichia coli]]
-[[Category: Cameron, A D.]]
+[[Category: Cameron, A D]]
-[[Category: Drew, D.]]
+[[Category: Drew, D]]
-[[Category: Iwata, S.]]
+[[Category: Iwata, S]]
-[[Category: Lee, C.]]
+[[Category: Lee, C]]
 [[Category: Membrane protein]]
 [[Category: Sodium proton antiporter]]
 [[Category: Transporter]]