2igx: Difference between revisions

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[[Image:2igx.gif|left|200px]]<br /><applet load="2igx" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:2igx.gif|left|200px]]
caption="2igx, resolution 1.70&Aring;" />
 
'''Achiral, Cheap and Potent Inhibitors of Plasmepsins II'''<br />
{{Structure
|PDB= 2igx |SIZE=350|CAPTION= <scene name='initialview01'>2igx</scene>, resolution 1.70&Aring;
|SITE=
|LIGAND= <scene name='pdbligand=A1T:5-PENTYL-N-{[4'-(PIPERIDIN-1-YLCARBONYL)BIPHENYL-4-YL]METHYL}-N-[1-(PYRIDIN-2-YLMETHYL)PIPERIDIN-4-YL]PYRIDINE-2-CARBOXAMIDE'>A1T</scene>
|ACTIVITY= [http://en.wikipedia.org/wiki/Plasmepsin_II Plasmepsin II], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.23.39 3.4.23.39]
|GENE=
}}
 
'''Achiral, Cheap and Potent Inhibitors of Plasmepsins II'''
 


==About this Structure==
==About this Structure==
2IGX is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Plasmodium_falciparum Plasmodium falciparum] with <scene name='pdbligand=A1T:'>A1T</scene> as [http://en.wikipedia.org/wiki/ligand ligand]. Active as [http://en.wikipedia.org/wiki/Plasmepsin_II Plasmepsin II], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.23.39 3.4.23.39] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2IGX OCA].  
2IGX is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Plasmodium_falciparum Plasmodium falciparum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2IGX OCA].  


==Reference==
==Reference==
Achiral, cheap, and potent inhibitors of Plasmepsins I, II, and IV., Boss C, Corminboeuf O, Grisostomi C, Meyer S, Jones AF, Prade L, Binkert C, Fischli W, Weller T, Bur D, ChemMedChem. 2006 Dec;1(12):1341-5. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=17091526 17091526]
Achiral, cheap, and potent inhibitors of Plasmepsins I, II, and IV., Boss C, Corminboeuf O, Grisostomi C, Meyer S, Jones AF, Prade L, Binkert C, Fischli W, Weller T, Bur D, ChemMedChem. 2006 Dec;1(12):1341-5. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/17091526 17091526]
[[Category: Plasmepsin II]]
[[Category: Plasmepsin II]]
[[Category: Plasmodium falciparum]]
[[Category: Plasmodium falciparum]]
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[[Category: achiral inhibitor]]
[[Category: achiral inhibitor]]


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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 17:29:33 2008''
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