4lcf: Difference between revisions
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{{STRUCTURE_4lcf| PDB=4lcf | SCENE= }} | |||
===Crystal structure of the Pseudomonas aeruginosa LPXC/LPC-014 complex=== | |||
{{ABSTRACT_PUBMED_23914798}} | |||
==Function== | |||
[[http://www.uniprot.org/uniprot/LPXC_PSEAE LPXC_PSEAE]] Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | |||
==About this Structure== | |||
[[4lcf]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Pseudomonas_aeruginosa_pao1 Pseudomonas aeruginosa pao1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4LCF OCA]. | |||
==Reference== | |||
<ref group="xtra">PMID:023914798</ref><references group="xtra"/><references/> | |||
[[Category: Pseudomonas aeruginosa pao1]] | |||
[[Category: Lee, C J.]] | |||
[[Category: Zhou, P.]] | |||
[[Category: Acyl udp-glcnac]] | |||
[[Category: Baab sandwich]] | |||
[[Category: Deacetylation]] | |||
[[Category: Hydrolase-antibiotic complex]] | |||
[[Category: Hydroxamate]] | |||
[[Category: Lipid a biosynthesis]] | |||
[[Category: Lipid a synthesis]] | |||
[[Category: Lpxc]] | |||
Revision as of 08:22, 21 August 2013
Crystal structure of the Pseudomonas aeruginosa LPXC/LPC-014 complex
Template:ABSTRACT PUBMED 23914798
Function
[LPXC_PSEAE] Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
About this Structure
4lcf is a 1 chain structure with sequence from Pseudomonas aeruginosa pao1. Full crystallographic information is available from OCA.
Reference
- Liang X, Lee CJ, Zhao J, Toone EJ, Zhou P. Synthesis, structure and antibiotic activity of aryl-substituted LpxC inhibitors. J Med Chem. 2013 Aug 5. PMID:23914798 doi:10.1021/jm4007774
