4lla: Difference between revisions
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{{STRUCTURE_4lla| PDB=4lla | SCENE= }} | |||
===Crystal structure of D3D4 domain of the LILRB2 molecule=== | |||
{{ABSTRACT_PUBMED_23955630}} | |||
==Function== | |||
[[http://www.uniprot.org/uniprot/LIRB2_HUMAN LIRB2_HUMAN]] Receptor for class I MHC antigens. Recognizes a broad spectrum of HLA-A, HLA-B, HLA-C and HLA-G alleles. Involved in the down-regulation of the immune response and the development of tolerance. Competes with CD8A for binding to class I MHC antigens. Inhibits FCGR1A-mediated phosphorylation of cellular proteins and mobilization of intracellular calcium ions.<ref>PMID:9548455</ref> <ref>PMID:9842885</ref> <ref>PMID:11875462</ref> <ref>PMID:12853576</ref> | |||
==About this Structure== | |||
[[4lla]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4LLA OCA]. | |||
==Reference== | |||
<ref group="xtra">PMID:023955630</ref><references group="xtra"/><references/> | |||
[[Category: Homo sapiens]] | |||
[[Category: Gao, G F.]] | |||
[[Category: Liu, J.]] | |||
[[Category: Nam, G.]] | |||
[[Category: Qi, J.]] | |||
[[Category: Ryu, M.]] | |||
[[Category: Shi, Y.]] | |||
[[Category: Song, H.]] | |||
[[Category: Wang, Q.]] | |||
[[Category: Yan, J.]] | |||
[[Category: Ig-like domain]] | |||
[[Category: Immune system]] | |||
[[Category: Immune-modulatory molecule]] | |||