2ioc: Difference between revisions

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[[Image:2ioc.jpg|left|200px]]<br /><applet load="2ioc" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:2ioc.jpg|left|200px]]
caption="2ioc, resolution 2.100&Aring;" />
 
'''The crystal structure of TREX1 explains the 3' nucleotide specificity and reveals a polyproline II helix for protein partenring'''<br />
{{Structure
|PDB= 2ioc |SIZE=350|CAPTION= <scene name='initialview01'>2ioc</scene>, resolution 2.100&Aring;
|SITE=
|LIGAND= <scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene> and <scene name='pdbligand=D5M:2'-DEOXYADENOSINE-5'-MONOPHOSPHATE'>D5M</scene>
|ACTIVITY= [http://en.wikipedia.org/wiki/Exodeoxyribonuclease_III Exodeoxyribonuclease III], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.11.2 3.1.11.2]
|GENE= Trex1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10090 Mus musculus])
}}
 
'''The crystal structure of TREX1 explains the 3' nucleotide specificity and reveals a polyproline II helix for protein partenring'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
2IOC is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus] with <scene name='pdbligand=MN:'>MN</scene> and <scene name='pdbligand=D5M:'>D5M</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/Exodeoxyribonuclease_III Exodeoxyribonuclease III], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.11.2 3.1.11.2] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2IOC OCA].  
2IOC is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2IOC OCA].  


==Reference==
==Reference==
The crystal structure of TREX1 explains the 3' nucleotide specificity and reveals a polyproline II helix for protein partnering., de Silva U, Choudhury S, Bailey SL, Harvey S, Perrino FW, Hollis T, J Biol Chem. 2007 Apr;282(14):10537-43. Epub 2007 Feb 9. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=17293595 17293595]
The crystal structure of TREX1 explains the 3' nucleotide specificity and reveals a polyproline II helix for protein partnering., de Silva U, Choudhury S, Bailey SL, Harvey S, Perrino FW, Hollis T, J Biol Chem. 2007 Apr;282(14):10537-43. Epub 2007 Feb 9. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/17293595 17293595]
[[Category: Exodeoxyribonuclease III]]
[[Category: Exodeoxyribonuclease III]]
[[Category: Mus musculus]]
[[Category: Mus musculus]]
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[[Category: proline helix]]
[[Category: proline helix]]


''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 17:54:33 2008''
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 17:31:47 2008''
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