2ish: Difference between revisions

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[[Image:2ish.gif|left|200px]]<br /><applet load="2ish" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:2ish.gif|left|200px]]
caption="2ish, resolution 2.00&Aring;" />
 
'''Botulinum Neurotoxin A Light Chain WT Crystal Form C'''<br />
{{Structure
|PDB= 2ish |SIZE=350|CAPTION= <scene name='initialview01'>2ish</scene>, resolution 2.00&Aring;
|SITE=
|LIGAND= <scene name='pdbligand=ZN:ZINC ION'>ZN</scene>
|ACTIVITY=
|GENE= bont/a, boNT/A ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1491 Clostridium botulinum])
}}
 
'''Botulinum Neurotoxin A Light Chain WT Crystal Form C'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
2ISH is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Clostridium_botulinum Clostridium botulinum] with <scene name='pdbligand=ZN:'>ZN</scene> as [http://en.wikipedia.org/wiki/ligand ligand]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ISH OCA].  
2ISH is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Clostridium_botulinum Clostridium botulinum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ISH OCA].  


==Reference==
==Reference==
Inhibition of metalloprotease botulinum serotype A from a pseudo-peptide binding mode to a small molecule that is active in primary neurons., Burnett JC, Ruthel G, Stegmann CM, Panchal RG, Nguyen TL, Hermone AR, Stafford RG, Lane DJ, Kenny TA, McGrath CF, Wipf P, Stahl AM, Schmidt JJ, Gussio R, Brunger AT, Bavari S, J Biol Chem. 2007 Feb 16;282(7):5004-14. Epub 2006 Nov 8. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=17092934 17092934]
Inhibition of metalloprotease botulinum serotype A from a pseudo-peptide binding mode to a small molecule that is active in primary neurons., Burnett JC, Ruthel G, Stegmann CM, Panchal RG, Nguyen TL, Hermone AR, Stafford RG, Lane DJ, Kenny TA, McGrath CF, Wipf P, Stahl AM, Schmidt JJ, Gussio R, Brunger AT, Bavari S, J Biol Chem. 2007 Feb 16;282(7):5004-14. Epub 2006 Nov 8. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/17092934 17092934]
[[Category: Clostridium botulinum]]
[[Category: Clostridium botulinum]]
[[Category: Single protein]]
[[Category: Single protein]]
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[[Category: botulinum neurotoxin]]
[[Category: botulinum neurotoxin]]


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