Bacteriophage repressor

<StructureSection load='1per' size='350' side='right' caption='Structure o phage 434 repressor cI protein complex with DNA (PDB entry 1per)' scene=>

The bacteriophage repressor controls the genetic switch determining the lytic cycle following phage infection. It competes with the Cro protein which selects for the lysogenic cycle. For details see Lambda repressor.

3D structures of bacteriophage repressor

Updated on 14-August-2014

Lambda repressor (LR)

1lrp – LR – Enterobacteria phage λ
2hnf, 2ho0 – LR (mutant)
1lmb, 1lli – LR + DNA

Lambda repressor cI protein

1f39, 1kca – LR C terminal
3kz3 – LR (mutant)
3bdn – LR (mutant) + DNA
1rio – LR N terminal + σ factor + DNA

Lambda repressor Cro protein

4cro, 5cro – LR N terminal
1orc, 1d1m, 1d1l, 2ecs, 2ovg – LR N terminal (mutant)
1cop – LR N terminal - NMR
2orc, 2a63 – LR N terminal (mutant) - NMR
6cro, 3orc – LR N terminal + DNA

Phage 434 repressor cI protein (434R)

1pra, 1r63, 2r63, 1sq8 – 434R N terminal - NMR
1r69 – 434R N terminal
2or1, 1per, 1rpe – 434R N terminal + DNA

Phage 434 repressor Cro protein (434R)

2cro – 434R
1zug – 434R N terminal - NMR
3cro – 434R N terminal + DNA

Mu bacteriophage repressor (MR)

1qpm – MR N terminal – NMR
1g4d – MR N terminal + DNA – NMR

186 bacteriophage repressor cI protein (186R)

2fjr – 186R (mutant)
2fkd – 186R C terminal
P22 repressor Cro protein (P22R)

P22 bacteriophage repressor (P22R)

1rzs – P22R N terminal – NMR

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Michal Harel, Alexander Berchansky