4bva: Difference between revisions
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{{STRUCTURE_4bva| PDB=4bva | SCENE= }} | |||
===Cristal structure of the NADPH-T3 form of mouse Mu-crystallin.=== | |||
{{ABSTRACT_PUBMED_24467707}} | |||
==Function== | |||
[[http://www.uniprot.org/uniprot/CRYM_MOUSE CRYM_MOUSE]] Specifically catalyzes the reduction of imine bonds in brain substrates that may include cystathionine ketimine (CysK) and lanthionine ketimine (LK). Binds thyroid hormone which is a strong reversible inhibitor. Presumably involved in the regulation of the free intracellular concentration of triiodothyronine and access to its nuclear receptors (By similarity). | |||
==About this Structure== | |||
[[4bva]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4BVA OCA]. | |||
==Reference== | |||
<ref group="xtra">PMID:024467707</ref><references group="xtra"/><references/> | |||
[[Category: Thiomorpholine-carboxylate dehydrogenase]] | |||
[[Category: Borel, F.]] | |||
[[Category: Ferrer, J L.]] | |||
[[Category: Gaillard, M C.]] | |||
[[Category: Hachi, I.]] | |||
[[Category: Palencia, A.]] | |||
[[Category: Oxidoreductase]] | |||
Revision as of 11:11, 5 February 2014
Cristal structure of the NADPH-T3 form of mouse Mu-crystallin.
Template:ABSTRACT PUBMED 24467707
Function
[CRYM_MOUSE] Specifically catalyzes the reduction of imine bonds in brain substrates that may include cystathionine ketimine (CysK) and lanthionine ketimine (LK). Binds thyroid hormone which is a strong reversible inhibitor. Presumably involved in the regulation of the free intracellular concentration of triiodothyronine and access to its nuclear receptors (By similarity).
About this Structure
4bva is a 2 chain structure. Full crystallographic information is available from OCA.
Reference
- Borel F, Hachi I, Palencia A, Gaillard MC, Ferrer JL. Crystal Structure of mouse Mu-crystallin complexed with NADPH and the T3 thyroid hormone. FEBS J. 2014 Jan 27. doi: 10.1111/febs.12726. PMID:24467707 doi:https://dx.doi.org/10.1111/febs.12726
