4k26: Difference between revisions
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{{STRUCTURE_4k26| PDB=4k26 | SCENE= }} | |||
===4,4-Dioxo-5,6-dihydro-[1,4,3]oxathiazines, a novel class of 11 -HSD1 inhibitors for the treatment of diabetes=== | |||
{{ABSTRACT_PUBMED_23845218}} | |||
==Function== | |||
[[http://www.uniprot.org/uniprot/DHI1_MOUSE DHI1_MOUSE]] Catalyzes reversibly the conversion of cortisol to the inactive metabolite cortisone. | |||
==About this Structure== | |||
[[4k26]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4K26 OCA]. | |||
==Reference== | |||
<ref group="xtra">PMID:023845218</ref><references group="xtra"/><references/> | |||
[[Category: 11-beta-hydroxysteroid dehydrogenase]] | |||
[[Category: Engel, C K.]] | |||
[[Category: Loenze, P.]] | |||
[[Category: Schimanski-Breves, S.]] | |||
[[Category: Vonderheyden, C.]] | |||
[[Category: Alpha and beta protein]] | |||
[[Category: Oxidoreductase]] | |||
[[Category: Oxidoreductase-oxidoreductase inhibitor complex]] | |||
[[Category: Short chain dehydrogenase]] | |||