2j0d: Difference between revisions

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[[Image:2j0d.gif|left|200px]]<br /><applet load="2j0d" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:2j0d.gif|left|200px]]
caption="2j0d, resolution 2.75&Aring;" />
 
'''CRYSTAL STRUCTURE OF HUMAN P450 3A4 IN COMPLEX WITH ERYTHROMYCIN'''<br />
{{Structure
|PDB= 2j0d |SIZE=350|CAPTION= <scene name='initialview01'>2j0d</scene>, resolution 2.75&Aring;
|SITE= <scene name='pdbsite=AC1:Ery+Binding+Site+For+Chain+A'>AC1</scene>
|LIGAND= <scene name='pdbligand=ERY:ERYTHROMYCIN+A'>ERY</scene> and <scene name='pdbligand=HEM:PROTOPORPHYRIN IX CONTAINING FE'>HEM</scene>
|ACTIVITY=
|GENE=
}}
 
'''CRYSTAL STRUCTURE OF HUMAN P450 3A4 IN COMPLEX WITH ERYTHROMYCIN'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
2J0D is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] with <scene name='pdbligand=ERY:'>ERY</scene> and <scene name='pdbligand=HEM:'>HEM</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. The following page contains interesting information on the relation of 2J0D with [[http://pdb.rcsb.org/pdb/static.do?p=education_discussion/molecule_of_the_month/pdb82_1.html Cytochrome p450]]. Known structural/functional Site: <scene name='pdbsite=AC1:Ery+Binding+Site+For+Chain+A'>AC1</scene>. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2J0D OCA].  
2J0D is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. The following page contains interesting information on the relation of 2J0D with [[http://pdb.rcsb.org/pdb/static.do?p=education_discussion/molecule_of_the_month/pdb82_1.html Cytochrome p450]]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2J0D OCA].  


==Reference==
==Reference==
Structural basis for ligand promiscuity in cytochrome P450 3A4., Ekroos M, Sjogren T, Proc Natl Acad Sci U S A. 2006 Sep 12;103(37):13682-7. Epub 2006 Sep 5. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=16954191 16954191]
Structural basis for ligand promiscuity in cytochrome P450 3A4., Ekroos M, Sjogren T, Proc Natl Acad Sci U S A. 2006 Sep 12;103(37):13682-7. Epub 2006 Sep 5. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/16954191 16954191]
[[Category: Cytochrome p450]]
[[Category: Cytochrome p450]]
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: transmembrane]]
[[Category: transmembrane]]


''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 17:57:57 2008''
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 17:35:43 2008''
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