2j0f: Difference between revisions

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[[Image:2j0f.jpg|left|200px]]<br /><applet load="2j0f" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:2j0f.jpg|left|200px]]
caption="2j0f, resolution 2.31&Aring;" />
 
'''STRUCTURAL BASIS FOR NON-COMPETITIVE PRODUCT INHIBITION IN HUMAN THYMIDINE PHOSPHORYLASE: IMPLICATION FOR DRUG DESIGN'''<br />
{{Structure
|PDB= 2j0f |SIZE=350|CAPTION= <scene name='initialview01'>2j0f</scene>, resolution 2.31&Aring;
|SITE= <scene name='pdbsite=AC1:Tdr+Binding+Site+For+Chain+C'>AC1</scene>
|LIGAND= <scene name='pdbligand=TDR:THYMINE'>TDR</scene>
|ACTIVITY= [http://en.wikipedia.org/wiki/Thymidine_phosphorylase Thymidine phosphorylase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.4.2.4 2.4.2.4]
|GENE=
}}
 
'''STRUCTURAL BASIS FOR NON-COMPETITIVE PRODUCT INHIBITION IN HUMAN THYMIDINE PHOSPHORYLASE: IMPLICATION FOR DRUG DESIGN'''
 


==Disease==
==Disease==
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==About this Structure==
==About this Structure==
2J0F is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] with <scene name='pdbligand=TDR:'>TDR</scene> as [http://en.wikipedia.org/wiki/ligand ligand]. Active as [http://en.wikipedia.org/wiki/Thymidine_phosphorylase Thymidine phosphorylase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.4.2.4 2.4.2.4] Known structural/functional Site: <scene name='pdbsite=AC1:Tdr+Binding+Site+For+Chain+C'>AC1</scene>. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2J0F OCA].  
2J0F is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2J0F OCA].  
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Single protein]]
[[Category: Single protein]]
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[[Category: transferase]]
[[Category: transferase]]


''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 17:58:01 2008''
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 17:35:56 2008''

Revision as of 15:35, 20 March 2008

File:2j0f.jpg


Drag the structure with the mouse to rotate
2j0f, resolution 2.31Å
Sites: AC1
Ligands: TDR
Activity: Thymidine phosphorylase, with EC number 2.4.2.4
Coordinates: save as pdb, mmCIF, xml



STRUCTURAL BASIS FOR NON-COMPETITIVE PRODUCT INHIBITION IN HUMAN THYMIDINE PHOSPHORYLASE: IMPLICATION FOR DRUG DESIGN


Disease

Known disease associated with this structure: Mitochondrial neurogastrointestinal encephalomyopathy syndrome OMIM:[131222]

About this Structure

2J0F is a Single protein structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.

Page seeded by OCA on Thu Mar 20 17:35:56 2008

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