2j1y: Difference between revisions

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[[Image:2j1y.gif|left|200px]]<br /><applet load="2j1y" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:2j1y.gif|left|200px]]
caption="2j1y, resolution 1.69&Aring;" />
 
'''HUMAN P53 CORE DOMAIN MUTANT M133L-V203A-N239Y-G245S-N268D'''<br />
{{Structure
|PDB= 2j1y |SIZE=350|CAPTION= <scene name='initialview01'>2j1y</scene>, resolution 1.69&Aring;
|SITE= <scene name='pdbsite=AC1:Ca+Binding+Site+For+Chain+D'>AC1</scene>
|LIGAND= <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene> and <scene name='pdbligand=CA:CALCIUM ION'>CA</scene>
|ACTIVITY=
|GENE=
}}
 
'''HUMAN P53 CORE DOMAIN MUTANT M133L-V203A-N239Y-G245S-N268D'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
2J1Y is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] with <scene name='pdbligand=ZN:'>ZN</scene> and <scene name='pdbligand=CA:'>CA</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Known structural/functional Site: <scene name='pdbsite=AC1:Ca+Binding+Site+For+Chain+D'>AC1</scene>. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2J1Y OCA].  
2J1Y is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2J1Y OCA].  


==Reference==
==Reference==
Structural basis for understanding oncogenic p53 mutations and designing rescue drugs., Joerger AC, Ang HC, Fersht AR, Proc Natl Acad Sci U S A. 2006 Oct 10;103(41):15056-61. Epub 2006 Oct 2. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=17015838 17015838]
Structural basis for understanding oncogenic p53 mutations and designing rescue drugs., Joerger AC, Ang HC, Fersht AR, Proc Natl Acad Sci U S A. 2006 Oct 10;103(41):15056-61. Epub 2006 Oct 2. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/17015838 17015838]
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Single protein]]
[[Category: Single protein]]
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[[Category: zinc]]
[[Category: zinc]]


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