4l4j: Difference between revisions

Revision as of 07:26, 28 August 2013

[IGHG2_HUMAN] Recurrent infections associated with rare immunoglobulin isotypes deficiency.

4l4j is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Vafa O, Gilliland GL, Brezski RJ, Strake B, Wilkinson T, Lacy ER, Scallon B, Teplyakov A, Malia TJ, Strohl WR. An engineered Fc variant of an IgG eliminates all immune effector functions via structural perturbations. Methods. 2013 Jul 17. pii: S1046-2023(13)00247-8. doi:, 10.1016/j.ymeth.2013.06.035. PMID:23872058 doi:10.1016/j.ymeth.2013.06.035

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-'''Unreleased structure'''
+{{STRUCTURE_4l4j|  PDB=4l4j  |  SCENE=  }}
+===Crystal structure of fc-fragment of human IgG2-Sigma antibody===
+{{ABSTRACT_PUBMED_23872058}}
-The entry 4l4j is ON HOLD  until Paper Publication
+==Disease==
+[[http://www.uniprot.org/uniprot/IGHG2_HUMAN IGHG2_HUMAN]] Recurrent infections associated with rare immunoglobulin isotypes deficiency.
-Authors: Teplyakov, A., Malia, T., Gillilang, G.
+==About this Structure==
+[[4l4j]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4L4J OCA].
-Description: Crystal structure of fc-fragment of human IgG2-Sigma antibody
+==Reference==
+<ref group="xtra">PMID:023872058</ref><references group="xtra"/><references/>
+[[Category: Homo sapiens]]
+[[Category: Gillilang, G.]]
+[[Category: Malia, T.]]
+[[Category: Teplyakov, A.]]
+[[Category: Immune system]]
+[[Category: Immunoglobulin fold]]