4l9c: Difference between revisions

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'''Unreleased structure'''
{{STRUCTURE_4l9c|  PDB=4l9c  |  SCENE=  }}
===Crystal structure of the FP domain of human F-box protein Fbxo7 (native)===


The entry 4l9c is ON HOLD  until Paper Publication
==Disease==
[[http://www.uniprot.org/uniprot/FBX7_HUMAN FBX7_HUMAN]] Parkinsonian-pyramidal syndrome. The disease is caused by mutations affecting the gene represented in this entry.


Authors: Du,Z., Huang,X., Shang,J., Yang,Y., Wang,G.
==Function==
[[http://www.uniprot.org/uniprot/FBX7_HUMAN FBX7_HUMAN]] Substrate recognition component of a SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Recognizes BIRC2 and DLGAP5.<ref>PMID:15145941</ref> <ref>PMID:16510124</ref> 


Description: Crystal structure of the FP domain of human F-box protein Fbxo7 (native)
==About this Structure==
[[4l9c]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4L9C OCA].
 
==Reference==
<references group="xtra"/><references/>
[[Category: Du,Z.]]
[[Category: Huang,X.]]
[[Category: Shang,J.]]
[[Category: Wang,G.]]
[[Category: Yang,Y.]]
[[Category: Alpha/beta fold]]
[[Category: Protein binding]]