4ljx: Difference between revisions
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{{STRUCTURE_4ljx| PDB=4ljx | SCENE= }} | |||
===Crystal structure of an AT-rich interactive domain-containing protein 3A (ARID3A) from Homo sapiens at 2.21 A resolution=== | |||
==Function== | |||
[[http://www.uniprot.org/uniprot/ARI3A_HUMAN ARI3A_HUMAN]] Transcription factor which may be involved in the control of cell cycle progression by the RB1/E2F1 pathway and in B-cell differentiation.<ref>PMID:11812999</ref> <ref>PMID:12692263</ref> | |||
==About this Structure== | |||
[[4ljx]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4LJX OCA]. | |||
==Reference== | |||
<references group="xtra"/><references/> | |||
[[Category: Homo sapiens]] | |||
[[Category: JCSG, Joint Center for Structural Genomics.]] | |||
[[Category: STEMCELL, Partnership for Stem Cell Biology.]] | |||
[[Category: Arid/bright dna binding domain]] | |||
[[Category: Jcsg]] | |||
[[Category: Joint center for structural genomic]] | |||
[[Category: Pf01388 family]] | |||
[[Category: Protein structure initiative]] | |||
[[Category: Psi-biology]] | |||
[[Category: Structural genomic]] | |||
[[Category: Transcription]] | |||
Revision as of 07:40, 28 August 2013
Crystal structure of an AT-rich interactive domain-containing protein 3A (ARID3A) from Homo sapiens at 2.21 A resolution
Function
[ARI3A_HUMAN] Transcription factor which may be involved in the control of cell cycle progression by the RB1/E2F1 pathway and in B-cell differentiation.[1] [2]
About this Structure
4ljx is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.
Reference
- ↑ Peeper DS, Shvarts A, Brummelkamp T, Douma S, Koh EY, Daley GQ, Bernards R. A functional screen identifies hDRIL1 as an oncogene that rescues RAS-induced senescence. Nat Cell Biol. 2002 Feb;4(2):148-53. PMID:11812999 doi:10.1038/ncb742
- ↑ Ma K, Araki K, Ichwan SJ, Suganuma T, Tamamori-Adachi M, Ikeda MA. E2FBP1/DRIL1, an AT-rich interaction domain-family transcription factor, is regulated by p53. Mol Cancer Res. 2003 Apr;1(6):438-44. PMID:12692263
