2mbc: Difference between revisions
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{{STRUCTURE_2mbc| PDB=2mbc | SCENE= }} | |||
===Solution Structure of human holo-PRL-3 in complex with vanadate=== | |||
==Function== | |||
[[http://www.uniprot.org/uniprot/TP4A3_HUMAN TP4A3_HUMAN]] Protein tyrosine phosphatase which stimulates progression from G1 into S phase during mitosis. Enhances cell proliferation, cell motility and invasive activity, and promotes cancer metastasis. May be involved in the progression of cardiac hypertrophy by inhibiting intracellular calcium mobilization in response to angiotensin II.<ref>PMID:11355880</ref> <ref>PMID:12782572</ref> | |||
==About this Structure== | |||
[[2mbc]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2MBC OCA]. | |||
==Reference== | |||
<references group="xtra"/><references/> | |||
[[Category: Homo sapiens]] | |||
[[Category: Protein-tyrosine-phosphatase]] | |||
[[Category: Jeon, Y H.]] | |||
[[Category: Jeong, K.]] | |||
[[Category: Jin, B.]] | |||
[[Category: Kang, D.]] | |||
[[Category: Kim, E.]] | |||
[[Category: Kim, J.]] | |||
[[Category: Kim, Y.]] | |||
[[Category: Lee, C.]] | |||
[[Category: Shin, S.]] | |||
[[Category: Holo-prl-3]] | |||
[[Category: Hydrolase]] | |||
[[Category: Vanadate]] | |||