4k06: Difference between revisions
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{{STRUCTURE_4k06| PDB=4k06 | SCENE= }} | |||
===Crystal structure of MTX-II from Bothrops brazili venom complexed with polyethylene glycol=== | |||
{{ABSTRACT_PUBMED_24145104}} | |||
==Function== | |||
[[http://www.uniprot.org/uniprot/PA2B1_BOTJR PA2B1_BOTJR]] Snake venom phospholipase A2 homolog that lacks enzymatic activity. In vivo, induces muscle necrosis, accompanied by polymorphonuclear cell infiltration, and edema in the mouse paw. Damages artificial and myoblast membranes by a calcium-independent mechanism. Has bactericidal activity.<ref>PMID:3176051</ref> <ref>PMID:11018293</ref> <ref>PMID:11829743</ref> <ref>PMID:12079495</ref> <ref>PMID:17346668</ref> <ref>PMID:18160090</ref> <ref>PMID:17157889</ref> | |||
==About this Structure== | |||
[[4k06]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Bothrops_jararacussu Bothrops jararacussu]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4K06 OCA]. | |||
==Reference== | |||
<ref group="xtra">PMID:024145104</ref><references group="xtra"/><references/> | |||
[[Category: Bothrops jararacussu]] | |||
[[Category: Borges, R J.]] | |||
[[Category: Comparetti, E J.]] | |||
[[Category: Fernandes, C A.H.]] | |||
[[Category: Fontes, M R.M.]] | |||
[[Category: Phospholipase a2]] | |||
[[Category: Toxin]] | |||