4l5s: Difference between revisions

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-'''Unreleased structure'''
+{{STRUCTURE_4l5s|  PDB=4l5s  |  SCENE=  }}
+===p202 HIN1 in complex with 12-mer dsDNA===
+{{ABSTRACT_PUBMED_23850291}}
-The entry 4l5s is ON HOLD
+==Function==
+[[http://www.uniprot.org/uniprot/IFI2_MOUSE IFI2_MOUSE]] Inhibits the transcriptional activity of several transcription factors, including NF-kappa-B p50 and p65, FOS, JUN, E2F1, E2F4, MYOD1 and myogenin. Has anti-apoptotic effects due to inhibition of the transcriptional activity of p53. Binds dsDNA in the cytosol. Is involved in innate immune response and has anti-inflammatory activity. Inhibits caspase activation in response to cytosolic DNA and may inhibit the activation of the AIM2 inflammasome, probably via association with AIM2.<ref>PMID:16670293</ref> <ref>PMID:19131592</ref>
-Authors: Yin, Q., Tian, Y., Wu, H.
+==About this Structure==
+[[4l5s]] is a 9 chain structure with sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4L5S OCA].
-Description: p202 HIN1 in complex with 12-mer dsDNA
+==Reference==
+<ref group="xtra">PMID:023850291</ref><references group="xtra"/><references/>
+[[Category: Mus musculus]]
+[[Category: Tian, Y.]]
+[[Category: Wu, H.]]
+[[Category: Yin, Q.]]
+[[Category: Dna binding protein-dna complex]]
+[[Category: Dsdna binding domain]]
+[[Category: Hin200]]
+[[Category: Ob fold]]

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