4i74: Difference between revisions

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{{STRUCTURE_4i74|  PDB=4i74  |  SCENE=  }}  
{{STRUCTURE_4i74|  PDB=4i74  |  SCENE=  }}  
===Crystal structure of the Trypanosoma brucei Inosine-Adenosine-Guanosine nucleoside hydrolase in complex with compound UAMC-00312 and allosterically inhibited by a Ni2+ ion===
===Crystal structure of the Trypanosoma brucei Inosine-Adenosine-Guanosine nucleoside hydrolase in complex with compound UAMC-00312 and allosterically inhibited by a Ni2+ ion===
{{ABSTRACT_PUBMED_16630632}}
{{ABSTRACT_PUBMED_23897478}}


==About this Structure==
==About this Structure==
[[4i74]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Trypanosoma_brucei_brucei_strain_927/4_gutat10.1 Trypanosoma brucei brucei strain 927/4 gutat10.1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4I74 OCA].  
[[4i74]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Tryb2 Tryb2]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4I74 OCA].  


==Reference==
==Reference==
<ref group="xtra">PMID:016630632</ref><references group="xtra"/><references/>
<ref group="xtra">PMID:023897478</ref><references group="xtra"/><references/>
[[Category: Purine nucleosidase]]
[[Category: Purine nucleosidase]]
[[Category: Trypanosoma brucei brucei strain 927/4 gutat10 1]]
[[Category: Tryb2]]
[[Category: Degano, M.]]
[[Category: Degano, M.]]
[[Category: Giannese, F.]]
[[Category: Giannese, F.]]

Revision as of 08:07, 18 December 2013

Template:STRUCTURE 4i74

Crystal structure of the Trypanosoma brucei Inosine-Adenosine-Guanosine nucleoside hydrolase in complex with compound UAMC-00312 and allosterically inhibited by a Ni2+ ion

Template:ABSTRACT PUBMED 23897478

About this Structure

4i74 is a 1 chain structure with sequence from Tryb2. Full crystallographic information is available from OCA.

Reference

  1. Giannese F, Berg M, Van der Veken P, Castagna V, Tornaghi P, Augustyns K, Degano M. Structures of purine nucleosidase from Trypanosoma brucei bound to isozyme-specific trypanocidals and a novel metalorganic inhibitor. Acta Crystallogr D Biol Crystallogr. 2013 Aug;69(Pt 8):1553-66. doi:, 10.1107/S0907444913010792. Epub 2013 Jul 20. PMID:23897478 doi:https://dx.doi.org/10.1107/S0907444913010792

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