4g3i: Difference between revisions

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~~{{STRUCTURE_4g3i| PDB~~=4g3i | ~~SCENE~~= }}

==Crystal structure of Dpo4 in complex with DNA duplex==

===~~Crystal~~ structure ~~of Dpo4 in complex~~ with DNA ~~duplex~~===

== Structural highlights ==

<table><tr><td colspan='2'>[[4g3i]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/Sulfolobus_solfataricus_p2 Sulfolobus solfataricus p2]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4G3I OCA]. For a guided tour on the structure components use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4G3I FirstGlance].

</td></tr><tr id='ligand'><td class="sblockLbl">[[Ligand|Ligands:]]</td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene></td></tr>

<tr id='related'><td class="sblockLbl">[[Related_structure|Related:]]</td><td class="sblockDat">[[2agq|2agq]]</td></tr>

<tr id='gene'><td class="sblockLbl">[[Gene|Gene:]]</td><td class="sblockDat">dbh, dpo4, SSO2448 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=273057 Sulfolobus solfataricus P2])</td></tr>

<tr id='activity'><td class="sblockLbl">Activity:</td><td class="sblockDat">[http://en.wikipedia.org/wiki/DNA-directed_DNA_polymerase DNA-directed DNA polymerase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.7.7 2.7.7.7] </td></tr>

<tr id='resources'><td class="sblockLbl">Resources:</td><td class="sblockDat">[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4g3i FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4g3i OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4g3i RCSB], [http://www.ebi.ac.uk/pdbsum/4g3i PDBsum]</td></tr>

</table>

==~~Function~~==

==See Also==

[[~~http://www.uniprot.org/uniprot/DPO4_SULSO DPO4_SULSO]] Poorly processive, error-prone~~ DNA polymerase ~~involved in untargeted mutagenesis. Copies undamaged~~ DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. It is involved in translesional synthesis.[HAMAP-Rule:MF_01113]

*[[DNA polymerase|DNA polymerase]]

__TOC__

~~==About this Structure==~~

</StructureSection>

~~[[4g3i]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki~~/~~Sulfolobus_solfataricus_p2 Sulfolobus solfataricus p2]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4G3I OCA].~~

[[Category: DNA-directed DNA polymerase]]

[[Category: Sulfolobus solfataricus p2]]

[[Category: Gan, J H.]]

[[Category: Gan, J H]]

[[Category: Huang, Z.]]

[[Category: Huang, Z]]

[[Category: Yan, Y Y.]]

[[Category: Yan, Y Y]]

[[Category: Dna synthesis]]

[[Category: Transferase-dna complex]]

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-{{STRUCTURE_4g3i|  PDB=4g3i  |  SCENE=  }}
+==Crystal structure of Dpo4 in complex with DNA duplex==
-===Crystal structure of Dpo4 in complex with DNA duplex===
+<StructureSection load='4g3i' size='340' side='right' caption='[[4g3i]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
+== Structural highlights ==
+<table><tr><td colspan='2'>[[4g3i]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/Sulfolobus_solfataricus_p2 Sulfolobus solfataricus p2]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4G3I OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4G3I FirstGlance]. <br>
+</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene></td></tr>
+<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2agq|2agq]]</td></tr>
+<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">dbh, dpo4, SSO2448 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=273057 Sulfolobus solfataricus P2])</td></tr>
+<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/DNA-directed_DNA_polymerase DNA-directed DNA polymerase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.7.7 2.7.7.7] </span></td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4g3i FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4g3i OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4g3i RCSB], [http://www.ebi.ac.uk/pdbsum/4g3i PDBsum]</span></td></tr>
+</table>
-==Function==
+==See Also==
-[[http://www.uniprot.org/uniprot/DPO4_SULSO DPO4_SULSO]] Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. It is involved in translesional synthesis.[HAMAP-Rule:MF_01113]
+*[[DNA polymerase|DNA polymerase]]
+__TOC__
-==About this Structure==
+</StructureSection>
-[[4g3i]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/Sulfolobus_solfataricus_p2 Sulfolobus solfataricus p2]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4G3I OCA].
 [[Category: DNA-directed DNA polymerase]]
 [[Category: Sulfolobus solfataricus p2]]
-[[Category: Gan, J H.]]
+[[Category: Gan, J H]]
-[[Category: Huang, Z.]]
+[[Category: Huang, Z]]
-[[Category: Yan, Y Y.]]
+[[Category: Yan, Y Y]]
 [[Category: Dna synthesis]]
 [[Category: Transferase-dna complex]]