2jev: Difference between revisions

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[[Image:2jev.jpg|left|200px]]<br /><applet load="2jev" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:2jev.jpg|left|200px]]
caption="2jev, resolution 2.30&Aring;" />
 
'''CRYSTAL STRUCTURE OF HUMAN SPERMINE,SPERMIDINE ACETYLTRANSFERASE IN COMPLEX WITH A BISUBSTRATE ANALOG (N1-ACETYLSPERMINE-S-COA).'''<br />
{{Structure
|PDB= 2jev |SIZE=350|CAPTION= <scene name='initialview01'>2jev</scene>, resolution 2.30&Aring;
|SITE= <scene name='pdbsite=AC1:Nhq+Binding+Site+For+Chain+A'>AC1</scene>
|LIGAND= <scene name='pdbligand=NHQ:(3R)-27-AMINO-3-HYDROXY-2,2-DIMETHYL-4,8,14-TRIOXO-12-THIA-5,9,15,19,24-PENTAAZAHEPTACOS-1-YL [(2S,3R,4S,5S)-5-(6-AMINO-9H-PURIN-9-YL)-4-HYDROXY-3-(PHOSPHONOOXY)TETRAHYDROFURAN-2-YL]METHYL DIHYDROGEN DIPHOSPHATE'>NHQ</scene>
|ACTIVITY= [http://en.wikipedia.org/wiki/Diamine_N-acetyltransferase Diamine N-acetyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.3.1.57 2.3.1.57]
|GENE=
}}
 
'''CRYSTAL STRUCTURE OF HUMAN SPERMINE,SPERMIDINE ACETYLTRANSFERASE IN COMPLEX WITH A BISUBSTRATE ANALOG (N1-ACETYLSPERMINE-S-COA).'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
2JEV is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] with <scene name='pdbligand=NHQ:'>NHQ</scene> as [http://en.wikipedia.org/wiki/ligand ligand]. Active as [http://en.wikipedia.org/wiki/Diamine_N-acetyltransferase Diamine N-acetyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.3.1.57 2.3.1.57] Known structural/functional Site: <scene name='pdbsite=AC1:Nhq+Binding+Site+For+Chain+A'>AC1</scene>. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2JEV OCA].  
2JEV is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2JEV OCA].  


==Reference==
==Reference==
Mechanistic and structural analysis of human spermidine/spermine N1-acetyltransferase., Hegde SS, Chandler J, Vetting MW, Yu M, Blanchard JS, Biochemistry. 2007 Jun 19;46(24):7187-95. Epub 2007 May 22. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=17516632 17516632]
Mechanistic and structural analysis of human spermidine/spermine N1-acetyltransferase., Hegde SS, Chandler J, Vetting MW, Yu M, Blanchard JS, Biochemistry. 2007 Jun 19;46(24):7187-95. Epub 2007 May 22. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/17516632 17516632]
[[Category: Diamine N-acetyltransferase]]
[[Category: Diamine N-acetyltransferase]]
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: transferase]]
[[Category: transferase]]


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