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{{STRUCTURE_4jyk|  PDB=4jyk  |  SCENE=  }}
==Structure of E. coli Transcriptional Regulator RutR with bound uracil==
===Structure of E. coli Transcriptional Regulator RutR with bound uracil===
<StructureSection load='4jyk' size='340' side='right' caption='[[4jyk]], [[Resolution|resolution]] 1.70&Aring;' scene=''>
 
== Structural highlights ==
==Function==
<table><tr><td colspan='2'>[[4jyk]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli_k-12 Escherichia coli k-12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4JYK OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4JYK FirstGlance]. <br>
[[http://www.uniprot.org/uniprot/RUTR_ECOLI RUTR_ECOLI]] Master transcription regulator which represses the degradation of pyrimidines (rutABCDEFG) and purines (gcl operon) for maintenance of metabolic balance between pyrimidines and purines. It also regulates the synthesis of pyrimidine nucleotides and arginine from glutamine (carAB) and the supply of glutamate (gadABWX).<ref>PMID:16540542</ref> <ref>PMID:17919280</ref>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=URA:URACIL'>URA</scene></td></tr>
 
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">b1013, JW0998, rutR, ycdC ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=83333 Escherichia coli K-12])</td></tr>
==About this Structure==
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4jyk FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4jyk OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4jyk RCSB], [http://www.ebi.ac.uk/pdbsum/4jyk PDBsum]</span></td></tr>
[[4jyk]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli_k-12 Escherichia coli k-12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4JYK OCA].  
</table>
 
__TOC__
==Reference==
</StructureSection>
<references group="xtra"/><references/>
[[Category: Escherichia coli k-12]]
[[Category: Escherichia coli k-12]]
[[Category: Almo, S C.]]
[[Category: Almo, S C]]
[[Category: Cooper, D R.]]
[[Category: Cooper, D R]]
[[Category: Knapik, A A.]]
[[Category: Knapik, A A]]
[[Category: Minor, W.]]
[[Category: Minor, W]]
[[Category: NYSGRC, New York Structural Genomics Research Consortium.]]
[[Category: Structural genomic]]
[[Category: Osinski,T.]]
[[Category: Osinski,T]]
[[Category: Petkowski, J J.]]
[[Category: Petkowski, J J]]
[[Category: Porebski, P J.]]
[[Category: Porebski, P J]]
[[Category: Helix-turn-helix]]
[[Category: Helix-turn-helix]]
[[Category: New york structural genomics research consortium]]
[[Category: Nysgrc]]
[[Category: Nysgrc]]
[[Category: Psi-biology]]
[[Category: Psi-biology]]
[[Category: Structural genomic]]
[[Category: Transcription regulator]]
[[Category: Transcription regulator]]
[[Category: Transcriptional regulator]]
[[Category: Transcriptional regulator]]