Matrix metalloproteinase: Difference between revisions
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[[Image: | <StructureSection load='M1.pdb' size='500' side='right' scene='MT1-MMP-TIMP-1_complex/Cv2/8' caption=''> | ||
{{ | [[Image:3ma2a.png|left|300px|thumb|MT1-MMP-TIMP-1 complex]] | ||
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'''Matrix metalloproteinases''' (MMP) are Zinc-dependent endopeptidases. MMP degrades extracellular matrix proteins. MMPs are produced by 28 different genes and are classified according to their protein substrates. They are inhibited by proteases called tissue inhibitors of metalloproteinase (TIMP). The pro-MMP contains a pro-peptide which must be removed to render the MMP active. See details of MMP12 in [[Matrix Metalloproteinase 12]]. More details of MMP in<br /> | '''Matrix metalloproteinases''' (MMP) are Zinc-dependent endopeptidases. MMP degrades extracellular matrix proteins. MMPs are produced by 28 different genes and are classified according to their protein substrates. They are inhibited by proteases called tissue inhibitors of metalloproteinase (TIMP). The pro-MMP contains a pro-peptide which must be removed to render the MMP active. See details of MMP12 in [[Matrix Metalloproteinase 12]]. More details of MMP in<br /> | ||
[[Matrix metalloproteinases]]<br /> | [[Matrix metalloproteinases]]<br /> | ||
