2jt2: Difference between revisions

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[[Image:2jt2.jpg|left|200px]]<br /><~~applet load~~=~~"2jt2" size~~=~~"350" color~~=~~"white" frame~~=~~"true" align="right" spinBox~~=~~"true"~~

[[Image:2jt2.jpg|left|200px]]

~~caption~~=~~"2jt2"~~ />

'''Solution Structure of the Aquifex aeolicus LpxC- CHIR-090 complex'''~~<br />~~

{{Structure

|PDB= 2jt2 |SIZE=350|CAPTION= <scene name='initialview01'>2jt2</scene>

|SITE=

|LIGAND= <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene> and <scene name='pdbligand=C90:N-{(1S,2R)-2-hydroxy-1-[(hydroxyamino)carbonyl]propyl}-4-{[4-(morpholin-4-ylmethyl)phenyl]ethynyl}benzamide'>C90</scene>

|ACTIVITY=

|GENE= lpxC, envA ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=63363 Aquifex aeolicus])

}}

'''Solution Structure of the Aquifex aeolicus LpxC- CHIR-090 complex'''

==Overview==

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==About this Structure==

2JT2 is a [~~http://en.wikipedia.org/wiki/Single_protein~~ Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Aquifex_aeolicus Aquifex aeolicus~~] with <scene name='pdbligand=ZN:'>ZN</scene> and <scene name='pdbligand=C90:'>C90</scene> as [http://en.wikipedia.org/wiki/ligands ligands~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2JT2 OCA].

2JT2 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Aquifex_aeolicus Aquifex aeolicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2JT2 OCA].

==Reference==

Structure of the deacetylase LpxC bound to the antibiotic CHIR-090: Time-dependent inhibition and specificity in ligand binding., Barb AW, Jiang L, Raetz CR, Zhou P, Proc Natl Acad Sci U S A. 2007 Nov 20;104(47):18433-8. Epub 2007 Nov 19. PMID:[http://~~ispc~~.~~weizmann~~.ac.~~il/~~/~~pmbin~~/~~getpm?pmid=~~18025458 18025458]

Structure of the deacetylase LpxC bound to the antibiotic CHIR-090: Time-dependent inhibition and specificity in ligand binding., Barb AW, Jiang L, Raetz CR, Zhou P, Proc Natl Acad Sci U S A. 2007 Nov 20;104(47):18433-8. Epub 2007 Nov 19. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/18025458 18025458]

[[Category: Aquifex aeolicus]]

[[Category: Single protein]]

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[[Category: hydrolase]]

[[Category: hydroxamate]]

[[Category: lipid a]]

[[Category: lipid some]]

[[Category: lipid a biosynthesis]]

[[Category: lipid synthesis]]

''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu ~~Feb 21 18~~:05:40 2008''

''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 17:44:51 2008''

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@@ Line 1: / Line 1: @@
-[[Image:2jt2.jpg|left|200px]]<br /><applet load="2jt2" size="350" color="white" frame="true" align="right" spinBox="true"
+[[Image:2jt2.jpg|left|200px]]
-caption="2jt2" />
-'''Solution Structure of the Aquifex aeolicus LpxC- CHIR-090 complex'''<br />
+ {{Structure
+|PDB= 2jt2 |SIZE=350|CAPTION= <scene name='initialview01'>2jt2</scene>
+|SITE=
+|LIGAND= <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene> and <scene name='pdbligand=C90:N-{(1S,2R)-2-hydroxy-1-[(hydroxyamino)carbonyl]propyl}-4-{[4-(morpholin-4-ylmethyl)phenyl]ethynyl}benzamide'>C90</scene>
+|ACTIVITY=
+|GENE= lpxC, envA ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=63363 Aquifex aeolicus])
+}}
+'''Solution Structure of the Aquifex aeolicus LpxC- CHIR-090 complex'''
 ==Overview==
@@ Line 7: / Line 16: @@
 ==About this Structure==
-JT2 is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Aquifex_aeolicus Aquifex aeolicus] with <scene name='pdbligand=ZN:'>ZN</scene> and <scene name='pdbligand=C90:'>C90</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2JT2 OCA].
+JT2 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Aquifex_aeolicus Aquifex aeolicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2JT2 OCA].
 ==Reference==
-Structure of the deacetylase LpxC bound to the antibiotic CHIR-090: Time-dependent inhibition and specificity in ligand binding., Barb AW, Jiang L, Raetz CR, Zhou P, Proc Natl Acad Sci U S A. 2007 Nov 20;104(47):18433-8. Epub 2007 Nov 19. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=18025458 18025458]
+Structure of the deacetylase LpxC bound to the antibiotic CHIR-090: Time-dependent inhibition and specificity in ligand binding., Barb AW, Jiang L, Raetz CR, Zhou P, Proc Natl Acad Sci U S A. 2007 Nov 20;104(47):18433-8. Epub 2007 Nov 19. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/18025458 18025458]
 [[Category: Aquifex aeolicus]]
 [[Category: Single protein]]
@@ Line 23: / Line 32: @@
 [[Category: hydrolase]]
 [[Category: hydroxamate]]
-[[Category: lipid a]]
+[[Category: lipid some]]
 [[Category: lipid a biosynthesis]]
 [[Category: lipid synthesis]]
-''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 18:05:40 2008''
+''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 17:44:51 2008''