2jtz: Difference between revisions

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[[Image:2jtz.jpg|left|200px]]<br /><applet load="2jtz" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:2jtz.jpg|left|200px]]
caption="2jtz" />
 
'''Solution structure and chemical shift assignments of the F104-to-5-flurotryptophan mutant of cardiac troponin C'''<br />
{{Structure
|PDB= 2jtz |SIZE=350|CAPTION= <scene name='initialview01'>2jtz</scene>
|SITE=  
|LIGAND=  
|ACTIVITY=  
|GENE= TNNC1, TNNC ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])
}}
 
'''Solution structure and chemical shift assignments of the F104-to-5-flurotryptophan mutant of cardiac troponin C'''
 


==Overview==
==Overview==
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==Disease==
==Disease==
Known diseases associated with this structure: Cardiomyopathy, familial hypertrophic, 192600 (3) OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=191040 191040]]
Known diseases associated with this structure: Cardiomyopathy, dilated, 1Z OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=191040 191040]], Cardiomyopathy, familial hypertrophic, 192600 (3) OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=191040 191040]]


==About this Structure==
==About this Structure==
2JTZ is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2JTZ OCA].  
2JTZ is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2JTZ OCA].  


==Reference==
==Reference==
Effects of Phe-to-Trp mutation and fluorotryptophan incorporation on the solution structure of cardiac troponin C, and analysis of its suitability as a potential probe for in situ NMR studies., Wang X, Mercier P, Letourneau PJ, Sykes BD, Protein Sci. 2005 Sep;14(9):2447-60. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=16131667 16131667]
Effects of Phe-to-Trp mutation and fluorotryptophan incorporation on the solution structure of cardiac troponin C, and analysis of its suitability as a potential probe for in situ NMR studies., Wang X, Mercier P, Letourneau PJ, Sykes BD, Protein Sci. 2005 Sep;14(9):2447-60. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/16131667 16131667]
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Single protein]]
[[Category: Single protein]]
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[[Category: polymorphism]]
[[Category: polymorphism]]


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