2kfn: Difference between revisions

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[[Image:2kfn.gif|left|200px]]<br /><applet load="2kfn" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:2kfn.gif|left|200px]]
caption="2kfn, resolution 2.03&Aring;" />
 
'''KLENOW FRAGMENT WITH BRIDGING-SULFUR SUBSTRATE AND MANGANESE'''<br />
{{Structure
|PDB= 2kfn |SIZE=350|CAPTION= <scene name='initialview01'>2kfn</scene>, resolution 2.03&Aring;
|SITE=
|LIGAND= <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene>, <scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene> and <scene name='pdbligand=MG:MAGNESIUM ION'>MG</scene>
|ACTIVITY= [http://en.wikipedia.org/wiki/DNA-directed_DNA_polymerase DNA-directed DNA polymerase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.7.7 2.7.7.7]
|GENE=
}}
 
'''KLENOW FRAGMENT WITH BRIDGING-SULFUR SUBSTRATE AND MANGANESE'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
2KFN is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli] with <scene name='pdbligand=ZN:'>ZN</scene>, <scene name='pdbligand=MN:'>MN</scene> and <scene name='pdbligand=MG:'>MG</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/DNA-directed_DNA_polymerase DNA-directed DNA polymerase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.7.7 2.7.7.7] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2KFN OCA].  
2KFN is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2KFN OCA].  


==Reference==
==Reference==
Structures of normal single-stranded DNA and deoxyribo-3'-S-phosphorothiolates bound to the 3'-5' exonucleolytic active site of DNA polymerase I from Escherichia coli., Brautigam CA, Sun S, Piccirilli JA, Steitz TA, Biochemistry. 1999 Jan 12;38(2):696-704. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=9888810 9888810]
Structures of normal single-stranded DNA and deoxyribo-3'-S-phosphorothiolates bound to the 3'-5' exonucleolytic active site of DNA polymerase I from Escherichia coli., Brautigam CA, Sun S, Piccirilli JA, Steitz TA, Biochemistry. 1999 Jan 12;38(2):696-704. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/9888810 9888810]
[[Category: DNA-directed DNA polymerase]]
[[Category: DNA-directed DNA polymerase]]
[[Category: Escherichia coli]]
[[Category: Escherichia coli]]
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[[Category: transferase]]
[[Category: transferase]]


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