4c2c: Difference between revisions
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{{STRUCTURE_4c2c| PDB=4c2c | SCENE= }} | |||
===Crystal structure of the protease CtpB in an active state=== | |||
{{ABSTRACT_PUBMED_24243021}} | |||
The | ==Function== | ||
[[http://www.uniprot.org/uniprot/CTPB_BACSU CTPB_BACSU]] Involved in the signal transduction pathway leading to the proteolytic activation of the mother cell transcription factor pro-sigma-K during sporulation. The signaling serine protease CtpB triggers pro-sigma-K processing by cleaving the regulatory protein SpoIVFA and is necessary for the proper timing of sigma-K activation.<ref>PMID:14526016</ref> <ref>PMID:16818230</ref> <ref>PMID:17557826</ref> | |||
==About this Structure== | |||
[[4c2c]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/ ] and [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4C2C OCA]. | |||
==Reference== | |||
<ref group="xtra">PMID:024243021</ref><references group="xtra"/><references/> | |||
[[Category: Escherichia coli]] | |||
[[Category: Clausen, T.]] | |||
[[Category: Heuck, A.]] | |||
[[Category: Kurzbauer, R.]] | |||
[[Category: Mastny, M.]] | |||
[[Category: Allosteric regulation]] | |||
[[Category: Conformational switch]] | |||
[[Category: Hydrolase]] | |||
[[Category: Pdz-protease]] | |||
[[Category: Proteolytic tunnel]] | |||
[[Category: Sporulation]] | |||