4c2s: Difference between revisions
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{{STRUCTURE_4c2s| PDB=4c2s | SCENE= }} | |||
===Crystal structure of the fucosylgalactoside alpha N- acetylgalactosaminyltransferase (GTA P156L mutant) in complex with UDP and deoxy-H-antigen acceptor=== | |||
The | ==Function== | ||
[[http://www.uniprot.org/uniprot/BGAT_HUMAN BGAT_HUMAN]] This protein is the basis of the ABO blood group system. The histo-blood group ABO involves three carbohydrate antigens: A, B, and H. A, B, and AB individuals express a glycosyltransferase activity that converts the H antigen to the A antigen (by addition of UDP-GalNAc) or to the B antigen (by addition of UDP-Gal), whereas O individuals lack such activity. | |||
==About this Structure== | |||
[[4c2s]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4C2S OCA]. | |||
[[Category: Homo sapiens]] | |||
[[Category: Henriksen, A.]] | |||
[[Category: Palcic, M.]] | |||
[[Category: Wedge, J T.]] | |||
[[Category: Abo]] | |||
[[Category: Blood group antigen]] | |||
[[Category: Glycosylation]] | |||
[[Category: Gta]] | |||
[[Category: Transferase]] | |||
Revision as of 05:29, 12 September 2013
Crystal structure of the fucosylgalactoside alpha N- acetylgalactosaminyltransferase (GTA P156L mutant) in complex with UDP and deoxy-H-antigen acceptor
Function
[BGAT_HUMAN] This protein is the basis of the ABO blood group system. The histo-blood group ABO involves three carbohydrate antigens: A, B, and H. A, B, and AB individuals express a glycosyltransferase activity that converts the H antigen to the A antigen (by addition of UDP-GalNAc) or to the B antigen (by addition of UDP-Gal), whereas O individuals lack such activity.
About this Structure
4c2s is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.
