4c39: Difference between revisions

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'''Unreleased structure'''
{{STRUCTURE_4c39|  PDB=4c39  |  SCENE=  }}
===Structure of rat neuronal nitric oxide synthase heme domain in complex with 6-((((3S, 5R)-5-(((6-amino-4-methylpyridin-2-yl)methoxy) methyl)pyrrolidin-3-yl)oxy)methyl)-4-methylpyridin-2-amine===
{{ABSTRACT_PUBMED_24660051}}


The entry 4c39 is ON HOLD  until Paper Publication
==Function==
[[http://www.uniprot.org/uniprot/NOS1_RAT NOS1_RAT]] Produces nitric oxide (NO) which is a messenger molecule with diverse functions throughout the body. In the brain and peripheral nervous system, NO displays many properties of a neurotransmitter. Inhibitory transmitter for non-adrenergic and non-cholinergic nerves in the colorectum. Probably has nitrosylase activity and mediates cysteine S-nitrosylation of cytoplasmic target proteins such SRR. Inhibitory transmitter for non-adrenergic and non-cholinergic nerves in the colorectum.


Authors: Li, H., Poulos, T.L.
==About this Structure==
[[4c39]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4C39 OCA].  


Description: Structure of rat neuronal nitric oxide synthase heme domain in complex with 6-((((3S, 5R)-5-(((6-amino-4-methylpyridin-2-yl)methoxy) methyl)pyrrolidin-3-yl)oxy)methyl)-4-methylpyridin-2-amine
==Reference==
<ref group="xtra">PMID:024660051</ref><references group="xtra"/><references/>
[[Category: Li, H.]]
[[Category: Poulos, T L.]]
[[Category: Inhibitor complex]]
[[Category: Oxidoreductase]]