4kc2: Difference between revisions
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{{STRUCTURE_4kc2| PDB=4kc2 | SCENE= }} | |||
===Structure of the blood group glycosyltransferase AAglyB in complex with a pyridine inhibitor as a neutral pyrophosphate surrogate=== | |||
The | ==Function== | ||
[[http://www.uniprot.org/uniprot/BGAT_HUMAN BGAT_HUMAN]] This protein is the basis of the ABO blood group system. The histo-blood group ABO involves three carbohydrate antigens: A, B, and H. A, B, and AB individuals express a glycosyltransferase activity that converts the H antigen to the A antigen (by addition of UDP-GalNAc) or to the B antigen (by addition of UDP-Gal), whereas O individuals lack such activity. | |||
==About this Structure== | |||
[[4kc2]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4KC2 OCA]. | |||
[[Category: Homo sapiens]] | |||
[[Category: Cuesta-Seijo, J A.]] | |||
[[Category: Lafont, D.]] | |||
[[Category: Palcic, M M.]] | |||
[[Category: Vidal, S.]] | |||
[[Category: Wang, S.]] | |||
[[Category: Blood group protein]] | |||
[[Category: Fuc-gal]] | |||
[[Category: Glycosyltransferase]] | |||
[[Category: Gta superfamily]] | |||
[[Category: Transferase-transferase inhibitor complex]] | |||
[[Category: Udp-gal]] | |||
[[Category: Udp-galnac]] | |||
Revision as of 05:32, 12 September 2013
Structure of the blood group glycosyltransferase AAglyB in complex with a pyridine inhibitor as a neutral pyrophosphate surrogate
Function
[BGAT_HUMAN] This protein is the basis of the ABO blood group system. The histo-blood group ABO involves three carbohydrate antigens: A, B, and H. A, B, and AB individuals express a glycosyltransferase activity that converts the H antigen to the A antigen (by addition of UDP-GalNAc) or to the B antigen (by addition of UDP-Gal), whereas O individuals lack such activity.
About this Structure
4kc2 is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.
