4kyp: Difference between revisions
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{{STRUCTURE_4kyp| PDB=4kyp | SCENE= }} | |||
===Beta-Scorpion Toxin folded in the periplasm of E.coli=== | |||
{{ABSTRACT_PUBMED_23999087}} | |||
==Function== | |||
[[http://www.uniprot.org/uniprot/SIXE_HOTJU SIXE_HOTJU]] Excitatory insect toxins induce a spastic paralysis. They bind voltage-independently at site-4 of sodium channels (Nav) and shift the voltage of activation toward more negative potentials thereby affecting sodium channel activation and promoting spontaneous and repetitive firing. This toxin is active only on insects. | |||
==About this Structure== | |||
[[4kyp]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4KYP OCA]. | |||
==Reference== | |||
<ref group="xtra">PMID:023999087</ref><references group="xtra"/><references/> | |||
[[Category: Cole, A R.]] | |||
[[Category: Lampert, A.]] | |||
[[Category: Lopes, J L.]] | |||
[[Category: Reilly, A OO.]] | |||
[[Category: Wallace, B A.]] | |||
[[Category: Alpha-beta]] | |||
[[Category: Toxin]] | |||
[[Category: Venom]] | |||
[[Category: Voltage gated na-channel]] | |||