4i14: Difference between revisions
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{{STRUCTURE_4i14| PDB=4i14 | SCENE= }} | {{STRUCTURE_4i14| PDB=4i14 | SCENE= }} | ||
===Crystal Structure of Mtb-ribA2 (Rv1415)=== | ===Crystal Structure of Mtb-ribA2 (Rv1415)=== | ||
{{ABSTRACT_PUBMED_23999287}} | |||
==Function== | ==Function== | ||
| Line 6: | Line 7: | ||
==About this Structure== | ==About this Structure== | ||
[[4i14]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/ | [[4i14]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Mycta Mycta]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4I14 OCA]. | ||
[[Category: | |||
==Reference== | |||
<ref group="xtra">PMID:023999287</ref><references group="xtra"/><references/> | |||
[[Category: Mycta]] | |||
[[Category: Gautam, R.]] | [[Category: Gautam, R.]] | ||
[[Category: Karthikeyan, S.]] | [[Category: Karthikeyan, S.]] | ||
Revision as of 09:09, 19 March 2014
Crystal Structure of Mtb-ribA2 (Rv1415)
Template:ABSTRACT PUBMED 23999287
Function
[RIBBA_MYCTA] Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity). Catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate (By similarity).
About this Structure
4i14 is a 2 chain structure with sequence from Mycta. Full crystallographic information is available from OCA.
Reference
- Singh M, Kumar P, Yadav S, Gautam R, Sharma N, Karthikeyan S. The crystal structure reveals the molecular mechanism of bifunctional 3,4-dihydroxy-2-butanone 4-phosphate synthase/GTP cyclohydrolase II (Rv1415) from Mycobacterium tuberculosis. Acta Crystallogr D Biol Crystallogr. 2013 Sep;69(Pt 9):1633-44. doi:, 10.1107/S0907444913011402. Epub 2013 Aug 15. PMID:23999287 doi:https://dx.doi.org/10.1107/S0907444913011402
