4m55: Difference between revisions

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~~{{STRUCTURE_4m55| PDB=4m55 | SCENE= }}~~

==Crystal structure of Human UDP-xylose synthase R236H substitution==

===Crystal structure of Human UDP-xylose synthase R236H substitution===

== Structural highlights ==

==~~Function~~==

<table><tr><td colspan='2'>[[4m55]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4M55 OCA]. For a guided tour on the structure components use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4M55 FirstGlance].

[[~~http://www.uniprot.org/uniprot/UXS1_HUMAN UXS1_HUMAN~~]] ~~Catalyzes the NAD-dependent decarboxylation of UDP-glucuronic acid to UDP-xylose. Necessary for the biosynthesis of the core tetrasaccharide in glycosaminoglycan biosynthesis~~.

</td></tr><tr id='ligand'><td class="sblockLbl">[[Ligand|Ligands:]]</td><td class="sblockDat"><scene name='pdbligand=NAD:NICOTINAMIDE-ADENINE-DINUCLEOTIDE'>NAD</scene>, <scene name='pdbligand=POP:PYROPHOSPHATE+2-'>POP</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=UDP:URIDINE-5-DIPHOSPHATE'>UDP</scene></td></tr>

<tr id='related'><td class="sblockLbl">[[Related_structure|Related:]]</td><td class="sblockDat">[[4lk3|4lk3]]</td></tr>

==~~About this Structure~~==

<tr id='gene'><td class="sblockLbl">[[Gene|Gene:]]</td><td class="sblockDat">UNQ2538/PRO6079, UXS, UXS1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])</td></tr>

[[4m55]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4M55 OCA].

<tr id='activity'><td class="sblockLbl">Activity:</td><td class="sblockDat">[http://en.wikipedia.org/wiki/UDP-glucuronate_decarboxylase UDP-glucuronate decarboxylase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.1.1.35 4.1.1.35] </td></tr>

<tr id='resources'><td class="sblockLbl">Resources:</td><td class="sblockDat">[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4m55 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4m55 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4m55 RCSB], [http://www.ebi.ac.uk/pdbsum/4m55 PDBsum]</td></tr>

</table>

__TOC__

</StructureSection>

[[Category: Homo sapiens]]

[[Category: UDP-glucuronate decarboxylase]]

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[[Category: Lyase]]

[[Category: Membrane]]

[[Category: ~~Rossman~~ fold]]

[[Category: Rossmann fold]]

[[Category: Short-chain dehydrogenase/reductase]]

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@@ Line 1: / Line 1: @@
-{{STRUCTURE_4m55|  PDB=4m55  |  SCENE=  }}
+==Crystal structure of Human UDP-xylose synthase R236H substitution==
-===Crystal structure of Human UDP-xylose synthase R236H substitution===
+<StructureSection load='4m55' size='340' side='right' caption='[[4m55]], [[Resolution|resolution]] 2.86&Aring;' scene=''>
+== Structural highlights ==
-==Function==
+<table><tr><td colspan='2'>[[4m55]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4M55 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4M55 FirstGlance]. <br>
-[[http://www.uniprot.org/uniprot/UXS1_HUMAN UXS1_HUMAN]] Catalyzes the NAD-dependent decarboxylation of UDP-glucuronic acid to UDP-xylose. Necessary for the biosynthesis of the core tetrasaccharide in glycosaminoglycan biosynthesis.
+</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=NAD:NICOTINAMIDE-ADENINE-DINUCLEOTIDE'>NAD</scene>, <scene name='pdbligand=POP:PYROPHOSPHATE+2-'>POP</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=UDP:URIDINE-5-DIPHOSPHATE'>UDP</scene></td></tr>
+<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4lk3|4lk3]]</td></tr>
-==About this Structure==
+<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">UNQ2538/PRO6079, UXS, UXS1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])</td></tr>
-[[4m55]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4M55 OCA].
+<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/UDP-glucuronate_decarboxylase UDP-glucuronate decarboxylase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.1.1.35 4.1.1.35] </span></td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4m55 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4m55 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4m55 RCSB], [http://www.ebi.ac.uk/pdbsum/4m55 PDBsum]</span></td></tr>
+</table>
+__TOC__
+</StructureSection>
 [[Category: Homo sapiens]]
 [[Category: UDP-glucuronate decarboxylase]]
@@ Line 15: / Line 19: @@
 [[Category: Lyase]]
 [[Category: Membrane]]
-[[Category: Rossman fold]]
+[[Category: Rossmann fold]]
 [[Category: Short-chain dehydrogenase/reductase]]