4c3d: Difference between revisions

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'''Unreleased structure'''
{{STRUCTURE_4c3d|  PDB=4c3d  |  SCENE=  }}
===HRSV M2-1, P422 crystal form===


The entry 4c3d is ON HOLD until Paper Publication
==Function==
[[http://www.uniprot.org/uniprot/M21_HRSVA M21_HRSVA]] Acts as a transcriptional elongation factor to prevent premature termination during transcription thus allowing complete synthesis of RSV mRNAs. Functions also as a processivity and antitermination factor to permit transit of the polymerase through intergenic regions to access promoter distal genes. Plays a role in the association of the matrix protein with the nucleocapsid, which initiates assembly and budding. Also, can activate NF-kappa-B through association with host RELA.<ref>PMID:8552680</ref> <ref>PMID:9420254</ref> <ref>PMID:10364337</ref>  


Authors: Tanner, S.J., Ariza, A., Richard, C.A., Wu, W., Trincao, J., Hiscox, J.A., Carroll, M., Sillman, N., Eleouet, J.F., Edwards, T.A., Barr, J.N.
==About this Structure==
[[4c3d]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4C3D OCA].  


Description: HRSV M2-1, P422 crystal form
==Reference==
<references group="xtra"/><references/>
[[Category: Ariza, A.]]
[[Category: Barr, J N.]]
[[Category: Carroll, M W.]]
[[Category: Edwards, T A.]]
[[Category: Eleouet, J F.]]
[[Category: Hiscox, J A.]]
[[Category: Richard, C A.]]
[[Category: Silman, N J.]]
[[Category: Tanner, S J.]]
[[Category: Trincao, J.]]
[[Category: Wu, W.]]
[[Category: M2-1 protein]]
[[Category: Viral protein]]