4c3e: Difference between revisions
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{{STRUCTURE_4c3e| PDB=4c3e | SCENE= }} | |||
===HRSV M2-1 mutant S58D S61D, P21 crystal=== | |||
==Function== | |||
[[http://www.uniprot.org/uniprot/M21_HRSVA M21_HRSVA]] Acts as a transcriptional elongation factor to prevent premature termination during transcription thus allowing complete synthesis of RSV mRNAs. Functions also as a processivity and antitermination factor to permit transit of the polymerase through intergenic regions to access promoter distal genes. Plays a role in the association of the matrix protein with the nucleocapsid, which initiates assembly and budding. Also, can activate NF-kappa-B through association with host RELA.<ref>PMID:8552680</ref> <ref>PMID:9420254</ref> <ref>PMID:10364337</ref> | |||
==About this Structure== | |||
[[4c3e]] is a 16 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4C3E OCA]. | |||
==Reference== | |||
<references group="xtra"/><references/> | |||
[[Category: Ariza, A.]] | |||
[[Category: Barr, J N.]] | |||
[[Category: Carroll, M W.]] | |||
[[Category: Edwards, T A.]] | |||
[[Category: Eleouet, J F.]] | |||
[[Category: Hiscox, J A.]] | |||
[[Category: Richard, C A.]] | |||
[[Category: Silman, N J.]] | |||
[[Category: Tanner, S J.]] | |||
[[Category: Trincao, J.]] | |||
[[Category: Wu, W.]] | |||
[[Category: Viral protein]] | |||