4lxs: Difference between revisions

Line 1:

~~'''Unreleased structure'''~~

===Structure of the Toll - Spatzle complex, a molecular hub in Drosophila development and innate immunity (glycosylated form)===

~~The entry 4lxs is ON HOLD~~ ~~until Paper Publication~~

==Function==

[[http://www.uniprot.org/uniprot/SPZ_DROME SPZ_DROME]] Component of the extracellular signaling pathway that establishes the dorsal-ventral pathway of the embryo. Three proteases; ndl, gd and snk process easter to create active easter. Active easter defines cell identities along the dorsal-ventral continuum by activating the spz ligand for the Tl receptor in the ventral region of the embryo. Spz C-106 in the hemolymph controls expression of the antifungal peptide Drosomycin (Drs) by acting as a ligand of Tl and inducing an intracellular signaling pathway.<ref>PMID:8124709</ref> <ref>PMID:11212919</ref> <ref>PMID:8808632</ref> <ref>PMID:12872120</ref>

~~Authors~~: ~~Stelter, M., Parthier, C~~.~~, Breithaupt, C~~.~~, Stubbs, M~~.T.

==About this Structure==

[[4lxs]] is a 3 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4LXS OCA].

~~Description~~: ~~Structure of the Toll~~ -~~Spatzle~~ complex~~, a molecular hub in Drosophila development and innate~~ immunity ~~(glycosylated form)~~

==Reference==

[[Category: Breithaupt, C.]]

[[Category: Parthier, C.]]

[[Category: Stelter, M.]]

[[Category: Stubbs, M T.]]

[[Category: Cytokine receptor]]

[[Category: Embryonic development]]

[[Category: Immune system]]

[[Category: Immune system-cytokine complex]]

[[Category: Innate immunity]]

[[Category: Leucine-rich repeat]]

[[Category: Receptor-ligand complex]]

[[Category: Tlr]]

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@@ Line 1: / Line 1: @@
-'''Unreleased structure'''
+{{STRUCTURE_4lxs|  PDB=4lxs  |  SCENE=  }}
+===Structure of the Toll - Spatzle complex, a molecular hub in Drosophila development and innate immunity (glycosylated form)===
-The entry 4lxs is ON HOLD  until Paper Publication
+==Function==
+[[http://www.uniprot.org/uniprot/SPZ_DROME SPZ_DROME]] Component of the extracellular signaling pathway that establishes the dorsal-ventral pathway of the embryo. Three proteases; ndl, gd and snk process easter to create active easter. Active easter defines cell identities along the dorsal-ventral continuum by activating the spz ligand for the Tl receptor in the ventral region of the embryo. Spz C-106 in the hemolymph controls expression of the antifungal peptide Drosomycin (Drs) by acting as a ligand of Tl and inducing an intracellular signaling pathway.<ref>PMID:8124709</ref> <ref>PMID:11212919</ref> <ref>PMID:8808632</ref> <ref>PMID:12872120</ref>
-Authors: Stelter, M., Parthier, C., Breithaupt, C., Stubbs, M.T.
+==About this Structure==
+[[4lxs]] is a 3 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4LXS OCA].
-Description: Structure of the Toll -Spatzle complex, a molecular hub in Drosophila development and innate immunity (glycosylated form)
+==Reference==
+<references group="xtra"/><references/>
+[[Category: Breithaupt, C.]]
+[[Category: Parthier, C.]]
+[[Category: Stelter, M.]]
+[[Category: Stubbs, M T.]]
+[[Category: Cytokine receptor]]
+[[Category: Embryonic development]]
+[[Category: Immune system]]
+[[Category: Immune system-cytokine complex]]
+[[Category: Innate immunity]]
+[[Category: Leucine-rich repeat]]
+[[Category: Receptor-ligand complex]]
+[[Category: Tlr]]