4m90: Difference between revisions
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{{STRUCTURE_4m90| PDB=4m90 | SCENE= }} | |||
===crystal structure of oxidized hN33/Tusc3=== | |||
The entry | ==Disease== | ||
[[http://www.uniprot.org/uniprot/TUSC3_HUMAN TUSC3_HUMAN]] Autosomal recessive nonsyndromic intellectual deficit. The disease is caused by mutations affecting the gene represented in this entry. | |||
==Function== | |||
[[http://www.uniprot.org/uniprot/TUSC3_HUMAN TUSC3_HUMAN]] Magnesium transporter. May be involved in N-glycosylation through its association with N-oligosaccharyl transferase.<ref>PMID:19717468</ref> | |||
==About this Structure== | |||
[[4m90]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4M90 OCA]. | |||
==Reference== | |||
<references group="xtra"/><references/> | |||
[[Category: Aebi, M.]] | |||
[[Category: Brozzo, M S.]] | |||
[[Category: Glockshuber, R.]] | |||
[[Category: Malojcic, G.]] | |||
[[Category: Mohorko, E.]] | |||
[[Category: Owen, R L.]] | |||
[[Category: Endoplasmic reticulum]] | |||
[[Category: Oxidoreductase]] | |||
[[Category: Redox active]] | |||
[[Category: Thioredoxin-like fold]] | |||
Revision as of 09:34, 26 March 2014
crystal structure of oxidized hN33/Tusc3
Disease
[TUSC3_HUMAN] Autosomal recessive nonsyndromic intellectual deficit. The disease is caused by mutations affecting the gene represented in this entry.
Function
[TUSC3_HUMAN] Magnesium transporter. May be involved in N-glycosylation through its association with N-oligosaccharyl transferase.[1]
About this Structure
4m90 is a 1 chain structure. Full crystallographic information is available from OCA.
Reference
- ↑ Zhou H, Clapham DE. Mammalian MagT1 and TUSC3 are required for cellular magnesium uptake and vertebrate embryonic development. Proc Natl Acad Sci U S A. 2009 Sep 15;106(37):15750-5. Epub 2009 Aug 26. PMID:19717468 doi:https://dx.doi.org/0908332106
