4m9j: Difference between revisions
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{{STRUCTURE_4m9j| PDB=4m9j | SCENE= }} | |||
===DNA Polymerase Beta E295K Soaked with dUMPNPP=== | |||
==Function== | |||
[[http://www.uniprot.org/uniprot/DPOLB_HUMAN DPOLB_HUMAN]] Repair polymerase that plays a key role in base-excision repair. Has 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity that removes the 5' sugar phosphate and also acts as a DNA polymerase that adds one nucleotide to the 3' end of the arising single-nucleotide gap. Conducts 'gap-filling' DNA synthesis in a stepwise distributive fashion rather than in a processive fashion as for other DNA polymerases.<ref>PMID:9207062</ref> <ref>PMID:9572863</ref> <ref>PMID:11805079</ref> <ref>PMID:21362556</ref> | |||
==About this Structure== | |||
[[4m9j]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4M9J OCA]. | |||
==Reference== | |||
<references group="xtra"/><references/> | |||
[[Category: Homo sapiens]] | |||
[[Category: Doublie , S.]] | |||
[[Category: Eckenroth, B E.]] | |||
[[Category: Dna complex]] | |||
[[Category: Dna polymerase]] | |||
[[Category: Lyase]] | |||
[[Category: Transferase-dna complex]] | |||
