4mfv: Difference between revisions
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{{STRUCTURE_4mfv| PDB=4mfv | SCENE= }} | |||
===Crystal structure of human CTNNBL1(residues 33~563)=== | |||
==Function== | |||
[[http://www.uniprot.org/uniprot/CTBL1_HUMAN CTBL1_HUMAN]] Component of the PRP19-CDC5L complex that forms an integral part of the spliceosome and is required for activating pre-mRNA splicing. Participates in AID/AICDA-mediated Ig class switching recombination (CSR). May induce apoptosis.<ref>PMID:12659813</ref> <ref>PMID:18722174</ref> | |||
==About this Structure== | |||
[[4mfv]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4MFV OCA]. | |||
==Reference== | |||
<references group="xtra"/><references/> | |||
[[Category: Ahn, J W.]] | |||
[[Category: Kim, K J.]] | |||
[[Category: Kim, S.]] | |||
[[Category: Arm repeat]] | |||
[[Category: Gene regulation]] | |||
Revision as of 14:00, 12 March 2014
Crystal structure of human CTNNBL1(residues 33~563)
Function
[CTBL1_HUMAN] Component of the PRP19-CDC5L complex that forms an integral part of the spliceosome and is required for activating pre-mRNA splicing. Participates in AID/AICDA-mediated Ig class switching recombination (CSR). May induce apoptosis.[1] [2]
About this Structure
4mfv is a 2 chain structure. Full crystallographic information is available from OCA.
Reference
- ↑ Jabbour L, Welter JF, Kollar J, Hering TM. Sequence, gene structure, and expression pattern of CTNNBL1, a minor-class intron-containing gene--evidence for a role in apoptosis. Genomics. 2003 Mar;81(3):292-303. PMID:12659813
- ↑ Conticello SG, Ganesh K, Xue K, Lu M, Rada C, Neuberger MS. Interaction between antibody-diversification enzyme AID and spliceosome-associated factor CTNNBL1. Mol Cell. 2008 Aug 22;31(4):474-84. doi: 10.1016/j.molcel.2008.07.009. PMID:18722174 doi:10.1016/j.molcel.2008.07.009
