4l0r: Difference between revisions
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==Crystal structure of FGF2-interacting protein from Homo sapiens. Northeast Structural Genomics Consortium Target HR9027A.== | |||
<StructureSection load='4l0r' size='340' side='right' caption='[[4l0r]], [[Resolution|resolution]] 2.49Å' scene=''> | |||
== Structural highlights == | |||
==Disease== | <table><tr><td colspan='2'>[[4l0r]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4L0R OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4L0R FirstGlance]. <br> | ||
</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">CEP57, KIAA0092, TSP57 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])</td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4l0r FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4l0r OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4l0r RCSB], [http://www.ebi.ac.uk/pdbsum/4l0r PDBsum]</span></td></tr> | |||
</table> | |||
== Disease == | |||
[[http://www.uniprot.org/uniprot/CEP57_HUMAN CEP57_HUMAN]] Mosaic variegated aneuploidy syndrome. The disease is caused by mutations affecting the gene represented in this entry. | [[http://www.uniprot.org/uniprot/CEP57_HUMAN CEP57_HUMAN]] Mosaic variegated aneuploidy syndrome. The disease is caused by mutations affecting the gene represented in this entry. | ||
== Function == | |||
==Function== | |||
[[http://www.uniprot.org/uniprot/CEP57_HUMAN CEP57_HUMAN]] Centrosomal protein which may be required for microtubule attachment to centrosomes. May act by forming ring-like structures around microtubules. Mediates nuclear translocation and mitogenic activity of the internalized growth factor FGF2, but that of FGF1.<ref>PMID:22321063</ref> | [[http://www.uniprot.org/uniprot/CEP57_HUMAN CEP57_HUMAN]] Centrosomal protein which may be required for microtubule attachment to centrosomes. May act by forming ring-like structures around microtubules. Mediates nuclear translocation and mitogenic activity of the internalized growth factor FGF2, but that of FGF1.<ref>PMID:22321063</ref> | ||
== References == | |||
== | <references/> | ||
__TOC__ | |||
</StructureSection> | |||
<references | |||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Acton, T B | [[Category: Acton, T B]] | ||
[[Category: Ciccosanti, C | [[Category: Ciccosanti, C]] | ||
[[Category: Everett, J K | [[Category: Everett, J K]] | ||
[[Category: Hunt, J F | [[Category: Hunt, J F]] | ||
[[Category: Lew, S | [[Category: Lew, S]] | ||
[[Category: Montelione, G T | [[Category: Montelione, G T]] | ||
[[Category: | [[Category: Structural genomic]] | ||
[[Category: Sahdev, S | [[Category: Sahdev, S]] | ||
[[Category: Seetharaman, J | [[Category: Seetharaman, J]] | ||
[[Category: Su, M | [[Category: Su, M]] | ||
[[Category: Tong, L | [[Category: Tong, L]] | ||
[[Category: Xiao, R | [[Category: Xiao, R]] | ||
[[Category: Cell cycle]] | [[Category: Cell cycle]] | ||
[[Category: Centrosomal protein]] | [[Category: Centrosomal protein]] | ||
[[Category: Cep57]] | [[Category: Cep57]] | ||
[[Category: Nesg]] | [[Category: Nesg]] | ||
[[Category: Psi-biology]] | [[Category: Psi-biology]] | ||
Revision as of 15:33, 21 December 2014
Crystal structure of FGF2-interacting protein from Homo sapiens. Northeast Structural Genomics Consortium Target HR9027A.
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