3zf8: Difference between revisions
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{{STRUCTURE_3zf8| PDB=3zf8 | SCENE= }} | |||
===Crystal structure of Saccharomyces cerevisiae Mnn9 in complex with GDP and Mn.=== | |||
{{ABSTRACT_PUBMED_24026536}} | |||
The | ==Function== | ||
[[http://www.uniprot.org/uniprot/MNN9_YEAST MNN9_YEAST]] The M-Pol I and M-Pol II complexes possess alpha-1,6-mannosyltransferase activity and are probably involved in the elongation of the mannan backbone of N-linked glycans on cell wall and periplasmic proteins. May also provide alpha-1,2-mannosyltransferase activity to the M-Pol I complex.<ref>PMID:12235155</ref> | |||
==About this Structure== | |||
[[3zf8]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae_s288c Saccharomyces cerevisiae s288c]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3ZF8 OCA]. | |||
==Reference== | |||
<ref group="xtra">PMID:024026536</ref><references group="xtra"/><references/> | |||
[[Category: Saccharomyces cerevisiae s288c]] | |||
[[Category: Aalten, D M.F van.]] | |||
[[Category: Schuettelkopf, A W.]] | |||
[[Category: Striebeck, A.]] | |||
[[Category: Transferase]] | |||
Revision as of 08:13, 29 September 2013
Crystal structure of Saccharomyces cerevisiae Mnn9 in complex with GDP and Mn.
Template:ABSTRACT PUBMED 24026536
Function
[MNN9_YEAST] The M-Pol I and M-Pol II complexes possess alpha-1,6-mannosyltransferase activity and are probably involved in the elongation of the mannan backbone of N-linked glycans on cell wall and periplasmic proteins. May also provide alpha-1,2-mannosyltransferase activity to the M-Pol I complex.[1]
About this Structure
3zf8 is a 1 chain structure with sequence from Saccharomyces cerevisiae s288c. Full crystallographic information is available from OCA.
Reference
- Striebeck A, Robinson DA, Schuttelkopf AW, van Aalten DM. Yeast Mnn9 is both a priming glycosyltransferase and an allosteric activator of mannan biosynthesis. Open Biol. 2013 Sep 11;3(9):130022. doi: 10.1098/rsob.130022. PMID:24026536 doi:10.1098/rsob.130022
- ↑ Stolz J, Munro S. The components of the Saccharomyces cerevisiae mannosyltransferase complex M-Pol I have distinct functions in mannan synthesis. J Biol Chem. 2002 Nov 22;277(47):44801-8. Epub 2002 Sep 15. PMID:12235155 doi:10.1074/jbc.M208023200
