2nz9: Difference between revisions

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[[Image:2nz9.jpg|left|200px]]<br /><applet load="2nz9" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:2nz9.jpg|left|200px]]
caption="2nz9, resolution 3.79&Aring;" />
 
'''Crystal structure of botulinum neurotoxin type A complexed with monoclonal antibody AR2'''<br />
{{Structure
|PDB= 2nz9 |SIZE=350|CAPTION= <scene name='initialview01'>2nz9</scene>, resolution 3.79&Aring;
|SITE=
|LIGAND= <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene> and <scene name='pdbligand=CA:CALCIUM ION'>CA</scene>
|ACTIVITY= [http://en.wikipedia.org/wiki/Bontoxilysin Bontoxilysin], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.24.69 3.4.24.69]
|GENE=
}}
 
'''Crystal structure of botulinum neurotoxin type A complexed with monoclonal antibody AR2'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
2NZ9 is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Clostridium_botulinum Clostridium botulinum] with <scene name='pdbligand=ZN:'>ZN</scene> and <scene name='pdbligand=CA:'>CA</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/Bontoxilysin Bontoxilysin], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.24.69 3.4.24.69] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2NZ9 OCA].  
2NZ9 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Clostridium_botulinum Clostridium botulinum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2NZ9 OCA].  


==Reference==
==Reference==
Molecular evolution of antibody cross-reactivity for two subtypes of type A botulinum neurotoxin., Garcia-Rodriguez C, Levy R, Arndt JW, Forsyth CM, Razai A, Lou J, Geren I, Stevens RC, Marks JD, Nat Biotechnol. 2007 Jan;25(1):107-16. Epub 2006 Dec 17. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=17173035 17173035]
Molecular evolution of antibody cross-reactivity for two subtypes of type A botulinum neurotoxin., Garcia-Rodriguez C, Levy R, Arndt JW, Forsyth CM, Razai A, Lou J, Geren I, Stevens RC, Marks JD, Nat Biotechnol. 2007 Jan;25(1):107-16. Epub 2006 Dec 17. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/17173035 17173035]
[[Category: Bontoxilysin]]
[[Category: Bontoxilysin]]
[[Category: Clostridium botulinum]]
[[Category: Clostridium botulinum]]
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[[Category: protein antibody complex]]
[[Category: protein antibody complex]]


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